Multiple Myeloma Symptomatic | Newly Diagnosed
Item
newly diagnosed with symptomatic multiple myeloma (mm)
boolean
C0026764 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C1518321 (UMLS CUI [2])
Multiple Myeloma Prior Therapy Systemic
Item
have not received any prior systemic anti-myeloma therapy
boolean
C0026764 (UMLS CUI [1,1])
C1514463 (UMLS CUI [1,2])
C0205373 (UMLS CUI [1,3])
Measurable Disease
Item
have measurable disease
boolean
C1513041 (UMLS CUI [1])
Patient unsuitable for procedure | Therapeutic procedure High dose | Stem cell transplant | Age | Comorbidity
Item
are not candidates for high-dose therapy plus stem-cell transplantation (sct) because of age (≥ 65 years) or coexisting conditions. refusal to undergo high dose therapy with sct is not sufficient for entry onto ca204-116 for a subject < 65 years old. there must be a comorbidity that prevents sct for a subject < 65 years old
boolean
C3839996 (UMLS CUI [1])
C0087111 (UMLS CUI [2,1])
C0444956 (UMLS CUI [2,2])
C1504389 (UMLS CUI [3])
C0001779 (UMLS CUI [4])
C0009488 (UMLS CUI [5])
Non-secretory myeloma | Multiple Myeloma-Light Chain Only
Item
non-secretory or oligo-secretory or free light-chain only myeloma
boolean
C0456845 (UMLS CUI [1])
C2347305 (UMLS CUI [2])
Smoldering myeloma | Asymptomatic multiple myeloma | Lytic lesion Absent
Item
smoldering mm, defined as asymptomatic mm with absence of lytic bone lesions
boolean
C1531608 (UMLS CUI [1])
C2585107 (UMLS CUI [2])
C0221204 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Monoclonal Gammopathy of Undetermined Significance
Item
monoclonal gammopathy of undetermined significance (mgus)
boolean
C0026470 (UMLS CUI [1])
Leukemia, Plasma Cell
Item
active plasma cell leukemia
boolean
C0023484 (UMLS CUI [1])
HIV Infection | Hepatitis A | Hepatitis B | Hepatitis C
Item
known human immunodeficiency virus (hiv) infection or active hepatitis a, b, or c
boolean
C0019693 (UMLS CUI [1])
C0019159 (UMLS CUI [2])
C0019163 (UMLS CUI [3])
C0019196 (UMLS CUI [4])