b-cell NHL
Item
histologically documented, aggressive and/ or intermediate grade and high-grade b cell nhl, cd20 positive.
boolean
C1512431 (UMLS CUI [1])
C1512858 (UMLS CUI [2])
chemotherapy
Item
in relapse after primary conventional chemotherapy
boolean
C0392920 (UMLS CUI [1])
tumor sensitive
Item
tumor sensitive (at least a partial response) to induction chemotherapy and/ or radiation therapy after treatment for relapse
boolean
C1704632 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C1704632 (UMLS CUI [2,1])
C1522449 (UMLS CUI [2,2])
treatment of cns or meningeal disease
Item
treatment of cns or meningeal disease (cytology-negative csf) if present
boolean
C0087111 (UMLS CUI [1,1])
C0007682 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0154728 (UMLS CUI [2,2])
doxorubicin dosage
Item
cumulative total doxorubicin dosage <500 mg/m2
boolean
C0013089 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
performance score
Item
performance score: 0-2
boolean
C1518965 (UMLS CUI [1])
prior malignancies
Item
prior malignancies eligible if treated for cure and without active disease
boolean
C0006826 (UMLS CUI [1])
pregnant or nursing
Item
patients must not be pregnant or nursing.
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
prior immunotherapy
Item
prior immunotherapy is allowed
boolean
C0021083 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])
signed informed consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
neutrophil count and platelet count
Item
absolute neutrophil count > 1500/ µl, platelet count >100,000/ µl
boolean
C0200633 (UMLS CUI [1])
C0005821 (UMLS CUI [2])
bilirubin and sgot
Item
bilirubin <1.5 x normal, sgot <2.5 x normal
boolean
C0005437 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
serum creatinine
Item
serum creatinine <1.5 mg/dl
boolean
C0201976 (UMLS CUI [1])
ejection fraction
Item
ejection fraction > 45% or > 40% with normal wall motion
boolean
C0232174 (UMLS CUI [1])
hiv negative
Item
hiv negative
boolean
C0481430 (UMLS CUI [1])
fev1
Item
fev1, dlco > 50% predicted
boolean
C0748133 (UMLS CUI [1])
pregnant or nursing
Item
pregnant or nursing
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])