Age
Item
age≥18；
boolean
C0001779 (UMLS CUI [1])
Myeloid Leukemia, Chronic
Item
the new diagnosis of cml patients in six months；
boolean
C0023473 (UMLS CUI [1])
Leukaemic infiltration extramedullary
Item
no proof of extra-medullary infiltration of leukemia；
boolean
C1868812 (UMLS CUI [1])
ECOG performance status
Item
ecog ps score：0-2；
boolean
C1520224 (UMLS CUI [1])
Liver function normal | Normal renal function | Serum total bilirubin measurement | Serum Alanine Transaminase tests | AST serum measurement | Creatinine measurement, serum | Upper Limit of Normal
Item
hepatic and renal functions are normal，serum bilirubin≤1.5*uln, serum alt and ast≤2.5*uln, serum cr≤1.5*uln;
boolean
C0232741 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
C0232805 (UMLS CUI [2])
C1278039 (UMLS CUI [3])
C0036828 (UMLS CUI [4])
C1261155 (UMLS CUI [5])
C0201976 (UMLS CUI [6])
C1519815 (UMLS CUI [7])
Therapeutic procedure Against Chronic Myeloid Leukemia
Item
do not receive the treatment of anti-cml；
boolean
C0087111 (UMLS CUI [1,1])
C0521124 (UMLS CUI [1,2])
C0023473 (UMLS CUI [1,3])
Informed Consent | Good Clinical Practice Requirement
Item
subjects signed informed consent form in line with gcp requirements。
boolean
C0021430 (UMLS CUI [1])
C2986419 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
pregnant or lactating women；
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Tyrosine kinase inhibitor
Item
received tkis any time before；
boolean
C1268567 (UMLS CUI [1])
Sepsis Control Unsuccessful | Multiple Organ Failure
Item
failure to control systemic infection or multiple organ failure；
boolean
C0243026 (UMLS CUI [1,1])
C0243148 (UMLS CUI [1,2])
C1272705 (UMLS CUI [1,3])
C0026766 (UMLS CUI [2])
Comorbidity Affecting Patient safety | Compliance behavior Limited
Item
according to the investigator's judgment, there are concomitant diseases with a serious safety hazard or affect the patients completed the study；
boolean
C0009488 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C1113679 (UMLS CUI [1,3])
C1321605 (UMLS CUI [2,1])
C0439801 (UMLS CUI [2,2])
Malignant Neoplasms Other
Item
being diagnosed with other malignancies in the prior 12 months；
boolean
C0006826 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
nervous system disorder | Mental disorders | Epilepsy | Dementia
Item
have a history of neurological or psychiatric disorders, including epilepsy or dementia；
boolean
C0027765 (UMLS CUI [1])
C0004936 (UMLS CUI [2])
C0014544 (UMLS CUI [3])
C0497327 (UMLS CUI [4])
Hypersensitivity imatinib
Item
known or suspected allergy to imatinib；
boolean
C0020517 (UMLS CUI [1,1])
C0935989 (UMLS CUI [1,2])
Body Surface Area
Item
bsa≤1.5m2；
boolean
C0005902 (UMLS CUI [1])
Investigational New Drugs Other | Study Subject Participation Status
Item
using other experimental drugs or participating in other clinical trials in the prior one months。
boolean
C0013230 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2348568 (UMLS CUI [2])