Estimated Glomerular Filtration Rate
Item
estimated glomerular filtration rate ≥45 ml/min/1.73m2
boolean
C3811844 (UMLS CUI [1])
Serum bicarbonate measurement
Item
serum bicarbonate 22-28 meq/l
boolean
C0428301 (UMLS CUI [1])
Diabetes Mellitus
Item
diabetes mellitus
boolean
C0011849 (UMLS CUI [1])
Uncontrolled hypertension | Titration Blood Pressure Pharmaceutical Preparations
Item
uncontrolled hypertension or recent (<3 weeks) titration of blood pressure medications
boolean
C1868885 (UMLS CUI [1])
C0162621 (UMLS CUI [2,1])
C0005823 (UMLS CUI [2,2])
C0013227 (UMLS CUI [2,3])
Fluid overload Clinical Significance | Physical Examination
Item
clinically significant volume overload on screening physical examination
boolean
C0546817 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C0031809 (UMLS CUI [2])
Disease | Kidney Diseases | Hypertensive disease | Malignant Neoplasms | Chronic Liver Failure | Chronic Obstructive Airway Disease Moderate | Chronic Obstructive Airway Disease Severe | Congestive heart failure New York Heart Association Classification | Obstructive Sleep Apnea Requirement Continuous Positive Airway Pressure at night
Item
selected medical conditions other than kidney disease and hypertension (active cancer, chronic liver failure, moderate to severe copd, new york heart association class 2 or greater congestive heart failure, obstructive sleep apnea requiring nightly continuous positive airway pressure)
boolean
C0012634 (UMLS CUI [1])
C0022658 (UMLS CUI [2])
C0020538 (UMLS CUI [3])
C0006826 (UMLS CUI [4])
C2936476 (UMLS CUI [5])
C0024117 (UMLS CUI [6,1])
C0205081 (UMLS CUI [6,2])
C0024117 (UMLS CUI [7,1])
C0205082 (UMLS CUI [7,2])
C0018802 (UMLS CUI [8])
C1275491 (UMLS CUI [9])
C0520679 (UMLS CUI [10,1])
C1514873 (UMLS CUI [10,2])
C0199451 (UMLS CUI [10,3])
C0240526 (UMLS CUI [10,4])
Alkali Supplementation
Item
use of alkali supplementation
boolean
C0002055 (UMLS CUI [1,1])
C0242297 (UMLS CUI [1,2])
Body mass index
Item
body mass index <18.5 or >40 kg/m2
boolean
C1305855 (UMLS CUI [1])
Ideal Body Weight
Item
ideal body weight <45.5 kg
boolean
C0421272 (UMLS CUI [1])
Anemia | Hematocrit level | Kidney Diseases | Healthy Volunteers
Item
anemia at screening (hematocrit <29% in participants with kidney disease or <33% in healthy participants)
boolean
C0002871 (UMLS CUI [1])
C0518014 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
C1708335 (UMLS CUI [4])
Alkali Supplements
Item
use of alkali supplements
boolean
C0002055 (UMLS CUI [1,1])
C0242295 (UMLS CUI [1,2])
Pregnancy | Breast Feeding
Item
pregnancy or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Hypersensitivity Food Study | Hypersensitivity Supplements | intolerance Food Study | intolerance Supplements
Item
allergy or intolerance of study foods or supplements
boolean
C0020517 (UMLS CUI [1,1])
C0016452 (UMLS CUI [1,2])
C2603343 (UMLS CUI [1,3])
C0020517 (UMLS CUI [2,1])
C0242295 (UMLS CUI [2,2])
C0231199 (UMLS CUI [3,1])
C0016452 (UMLS CUI [3,2])
C2603343 (UMLS CUI [3,3])
C0231199 (UMLS CUI [4,1])
C0242295 (UMLS CUI [4,2])