Eligibility Determination Checklist
Item
an associate investigator will examine participants and determine their eligibility according to the inclusion and exclusion criteria as documented by the eligibility checklist.
boolean
C0013893 (UMLS CUI [1,1])
C1707357 (UMLS CUI [1,2])
Gender | Age
Item
men and women between the ages 55-70 years
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
General health good Physical Examination
Item
in good general health as determined by physical exam and normal ranges obtained during screening
boolean
C1277245 (UMLS CUI [1,1])
C0031809 (UMLS CUI [1,2])
Postmenopausal state | Menstruation
Item
post-menopausal women (no menses within 12 months)
boolean
C0232970 (UMLS CUI [1])
C0025344 (UMLS CUI [2])
Normal blood pressure | Prehypertension | Systolic Pressure | Diastolic blood pressure
Item
normal or pre-hypertensive blood pressure (e.g., sbp less than or equal to 139 mmhg and dbp less than or equal to 89 mmhg)
boolean
C2712122 (UMLS CUI [1])
C1696708 (UMLS CUI [2])
C0871470 (UMLS CUI [3])
C0428883 (UMLS CUI [4])
Hyperlipidemia Normal | Hyperlipidemia Mild | Total cholesterol | Low-Density Lipoproteins | Triglycerides | High Density Lipoproteins
Item
normal or mild hyperlipidemia (e.g., tc less than or equal to 239, ldl less than or equal to159, triglycerides less than or equal to 199, hdl < 45 mg/dl)
boolean
C0020473 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
C0020473 (UMLS CUI [2,1])
C2945599 (UMLS CUI [2,2])
C0543421 (UMLS CUI [3])
C0023823 (UMLS CUI [4])
C0041004 (UMLS CUI [5])
C0023821 (UMLS CUI [6])
Body mass index
Item
bmi between 18.5 to 25kg/m2
boolean
C1305855 (UMLS CUI [1])
Informed Consent
Item
willing and ability to sign consent
boolean
C0021430 (UMLS CUI [1])
Time commitment Study
Item
willing to make time commitment for study
boolean
C0040223 (UMLS CUI [1,1])
C0870312 (UMLS CUI [1,2])
C2603343 (UMLS CUI [1,3])
Able to speak fluently English Language
Item
individuals who are fluent in english
boolean
C0564241 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
Progressive Disease | Disease Unstable status | Cardiovascular Diseases | Lung diseases | Gastrointestinal Diseases | CNS disorder | Mental disorders | Endocrine System Diseases | Hematological Disease | Kidney Diseases | Immune System Diseases
Item
progressive or unstable known disease of any body system including cardiovascular, pulmonary, gastrointestinal, central nervous system, psychiatric, endocrine, hematologic, renal, or immunologic disorders
boolean
C1335499 (UMLS CUI [1])
C0012634 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C0007222 (UMLS CUI [3])
C0024115 (UMLS CUI [4])
C0017178 (UMLS CUI [5])
C0007682 (UMLS CUI [6])
C0004936 (UMLS CUI [7])
C0014130 (UMLS CUI [8])
C0018939 (UMLS CUI [9])
C0022658 (UMLS CUI [10])
C0021053 (UMLS CUI [11])
Inflammatory disorder | Rheumatoid Arthritis | Lupus Erythematosus, Systemic | Hepatitis
Item
known acute and chronic inflammatory disease (i.e. rheumatoid arthritis, systemic lupus erythematous, hepatitis)
boolean
C1290884 (UMLS CUI [1])
C0003873 (UMLS CUI [2])
C0024141 (UMLS CUI [3])
C0019158 (UMLS CUI [4])
Elevated C-reactive protein level
Item
elevated c-reactive protein level (> 3.0mg/l)
boolean
C4023452 (UMLS CUI [1])
Smoking
Item
current (or within the last 3 months) smoking of any tobacco products, i.e., cigarettes, pipe
boolean
C0037369 (UMLS CUI [1])
Comprehensive metabolic panel abnormal | Complete Blood Count abnormal | Cholesterol abnormal | Thyroid stimulating hormone measurement abnormal | ESR abnormal
Item
abnormal complete metabolic panel (cmp), complete blood count (cbc), cholesterol panel, thyroid stimulating hormone (tsh), erythrocyte sedimentation rate (esr) --
boolean
C0519825 (UMLS CUI [1,1])
C0205161 (UMLS CUI [1,2])
C0009555 (UMLS CUI [2,1])
C0205161 (UMLS CUI [2,2])
C0008377 (UMLS CUI [3,1])
C0205161 (UMLS CUI [3,2])
C0202230 (UMLS CUI [4,1])
C0205161 (UMLS CUI [4,2])
C0438217 (UMLS CUI [5])
Laboratory Results abnormal | older adults
Item
(laboratory values outside of acceptable reference range for older adults if determined to
boolean
C1254595 (UMLS CUI [1,1])
C0205161 (UMLS CUI [1,2])
C0001792 (UMLS CUI [2])
Laboratory Test Result Clinically Significant
Item
be clinically significant)
boolean
C2826633 (UMLS CUI [1])
Indication Substance Use Disorders
Item
indications of current or within last 3 years substance or alcohol abuse
boolean
C3146298 (UMLS CUI [1,1])
C0038586 (UMLS CUI [1,2])
Alcohol consumption | Beer | Wine | Hard liquor intake
Item
alcohol consumption > 1 drink/day, i.e., 1 bottle of beer, half glass of wine, 1 shot hard liquor
boolean
C0001948 (UMLS CUI [1])
C0004922 (UMLS CUI [2])
C0043188 (UMLS CUI [3])
C0559433 (UMLS CUI [4])
Hypersensitivity Cherry cake | Hypersensitivity Aronia Berries
Item
known sensitivity or allergy to tart cherry or aroniaberry
boolean
C0020517 (UMLS CUI [1,1])
C0452601 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C1215581 (UMLS CUI [2,2])
C0005135 (UMLS CUI [2,3])
Anticholesteremic Agents | Antihypertensive Agents | Thyroid preparations | Steroid drugs | Hormone preparation
Item
currently on cholesterol-lowering, anti-hypertensive, thyroid, steroid or hormonal medications
boolean
C0003277 (UMLS CUI [1])
C0003364 (UMLS CUI [2])
C0279175 (UMLS CUI [3])
C0260264 (UMLS CUI [4])
C0019928 (UMLS CUI [5])
Continuous use of drugs | Vitamins | oral supplement | Drugs, Non-Prescription | Aspirin or aspirin-containing product | Anti-Inflammatory Agents, Non-Steroidal | Motrin | Advil | Aleve
Item
routine use of vitamins, supplements, or over the counter medications including aspirin, aspirin-containing products, non-steroidal anti-inflammatory drugs (nsaids), i.e., motrin, advil, aleve, unless they were discontinued 14 days prior to their first visit.
boolean
C1562611 (UMLS CUI [1])
C0042890 (UMLS CUI [2])
C0351437 (UMLS CUI [3])
C0013231 (UMLS CUI [4])
C3843719 (UMLS CUI [5])
C0003211 (UMLS CUI [6])
C0699203 (UMLS CUI [7])
C0593507 (UMLS CUI [8])
C0718343 (UMLS CUI [9])