Gender | Adult | Asians | Recurrent disease | Neoplasm Metastasis | curative treatment
Item
adult asian women with locoregionally recurrent or metastatic disease not amenable to curative therapy
boolean
C0079399 (UMLS CUI [1])
C0001675 (UMLS CUI [2])
C0078988 (UMLS CUI [3])
C0277556 (UMLS CUI [4])
C0027627 (UMLS CUI [5])
C1273390 (UMLS CUI [6])
Breast Carcinoma Positive
Item
confirmed diagnosis of er positive breast cancer
boolean
C0678222 (UMLS CUI [1,1])
C1446409 (UMLS CUI [1,2])
cancer treatment Systemic Previous | Estrogen receptor positive tumor Advanced phase
Item
no prior systemic anti-cancer therapy for advanced er+ disease
boolean
C0920425 (UMLS CUI [1,1])
C0205373 (UMLS CUI [1,2])
C0205156 (UMLS CUI [1,3])
C1562312 (UMLS CUI [2,1])
C0205179 (UMLS CUI [2,2])
Postmenopausal state
Item
postmenopausal women
boolean
C0232970 (UMLS CUI [1])
Measurable Disease Response Evaluation Criteria in Solid Tumors | Bone Diseases
Item
measurable disease as per response evaluation criterion in solid tumors [recist] or bone-only disease
boolean
C1513041 (UMLS CUI [1,1])
C1709926 (UMLS CUI [1,2])
C0005940 (UMLS CUI [2])
ECOG performance status
Item
eastern cooperative oncology group [ecog] 0-1
boolean
C1520224 (UMLS CUI [1])
body system or organ function Adequate | Bone Marrow Function Adequate
Item
adequate organ and marrow function
boolean
C0678852 (UMLS CUI [1,1])
C0205411 (UMLS CUI [1,2])
C0005953 (UMLS CUI [2,1])
C0542341 (UMLS CUI [2,2])
C0205411 (UMLS CUI [2,3])
Agree Providing Tumor tissue sample
Item
patient must agree to provide tumor tissue
boolean
C3641827 (UMLS CUI [1,1])
C1999230 (UMLS CUI [1,2])
C0475358 (UMLS CUI [1,3])
erbB-2 Receptor Positive Disease
Item
confirmed diagnosis of her2 positive disease
boolean
C0069515 (UMLS CUI [1,1])
C1446409 (UMLS CUI [1,2])
C0012634 (UMLS CUI [1,3])
Visceral Neoplasm Metastasis Advanced phase Symptomatic | Complication Life Threatening
Item
patients with advanced, symptomatic, visceral spread that are at risk of life threatening complication in the short term
boolean
C0442045 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
C0205179 (UMLS CUI [1,3])
C0231220 (UMLS CUI [1,4])
C0009566 (UMLS CUI [2,1])
C2826244 (UMLS CUI [2,2])
CNS metastases Uncontrolled | CNS metastases Symptomatic
Item
known uncontrolled or symptomatic cns metastases
boolean
C0686377 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0686377 (UMLS CUI [2,1])
C0231220 (UMLS CUI [2,2])
Neoadjuvant Therapy | Adjuvant therapy | Non-Steroidal Aromatase Inhibitor | anastrozole | letrozole | Disease recurrence
Item
prior neoadjuvant or adjuvant treatment with a non steroidal aromatase inhibitor (ie, anastrozole or letrozole) with disease recurrence while on or within 12 months of completing treatment
boolean
C0600558 (UMLS CUI [1])
C0677850 (UMLS CUI [2])
C1518386 (UMLS CUI [3])
C0290883 (UMLS CUI [4])
C0246421 (UMLS CUI [5])
C0679254 (UMLS CUI [6])
Prior Therapy Cyclin-Dependent Kinase Inhibitor Agents
Item
prior treatment with any cdk 4/6 inhibitor
boolean
C1514463 (UMLS CUI [1,1])
C1511576 (UMLS CUI [1,2])