ID.1
Item
patients (>= 18 years) with non-resectable metastasized or recurrent histologically proven crc with the presence of a reference lesion two-dimensional measurable and accessible for a biopsy
boolean
C0001779 (UMLS CUI [1])
C1513041 (UMLS CUI [2])
C1300072 (UMLS CUI [3,1])
C0019638 (UMLS CUI [3,2])
ID.2
Item
a performance status who 0-2 (karnofsky >= 60%)
boolean
C0206065 (UMLS CUI [1])
ID.3
Item
an estimated life expectancy of at least 3 months
boolean
C0023671 (UMLS CUI [1])
ID.4
Item
written informed consent
boolean
C0021430 (UMLS CUI [1])
ID.5
Item
patients older than 75 years not fulfilling these criteria
boolean
C0001779 (UMLS CUI [1])
ID.6
Item
brain metastases or a secondary cane
boolean
C0220650 (UMLS CUI [1])
C2939419 (UMLS CUI [2])
ID.7
Item
a history of a systemic palliative chemotherapy
boolean
C0392920 (UMLS CUI [1,1])
C1285530 (UMLS CUI [1,2])
ID.8
Item
and an adjuvant chemotherapy (within 6 months)
boolean
C1522673 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
ID.9
Item
pregnant or nursing women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
ID.10
Item
a known allergy toward irinotecanhydroclorid or of any ingredients of campto or other severe medical
boolean
C0020517 (UMLS CUI [1,1])
C0123931 (UMLS CUI [1,2])
ID.11
Item
laboratory and social conditions not allowing chemotherapy and follow-up
boolean
C1254595 (UMLS CUI [1])
C0037438 (UMLS CUI [2])