age
Item
woman aged 18 years or older.
boolean
C0001779 (UMLS CUI [1])
breast cancer
Item
confirmed pathologic diagnosis of breast cancer
boolean
C0678222 (UMLS CUI [1])
recurrent breast cancer
Item
locally advanced, metastatic, or locoregional recurrent breast cancer not amenable to curative treatment with surgery or radiotherapy.
boolean
C0278493 (UMLS CUI [1])
surgically sterile or postmenopausal woman
Item
surgically sterile or postmenopausal woman
boolean
C0021359 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
er+ and/or pgr+ and erbb2- tumor
Item
documented er+ and/or pgr+ and erbb2- tumor
boolean
C2938924 (UMLS CUI [1])
C2367479 (UMLS CUI [2])
advanced or metastatic disease
Item
progression of locally advanced or metastatic disease during treatment with a nonsteroidal ai or tamoxifen, or progression during treatment with (or within 6 months of discontinuation of) an adjuvant nonsteroidal ai.
boolean
C0027627 (UMLS CUI [1])
C0039286 (UMLS CUI [2])
exemestane, bosutinib
Item
prior exemestane, prior bosutinib, or any other prior anti-src therapy.
boolean
C0060116 (UMLS CUI [1])
C1831731 (UMLS CUI [2])
endocrine treatment
Item
more than 1 prior endocrine treatment for locally advanced or mbc
boolean
C0038900 (UMLS CUI [1])
cytotoxic chemotherapy
Item
more than 1 prior cytotoxic chemotherapy regimen in metastatic setting.
boolean
C0677881 (UMLS CUI [1])
bone or skin
Item
bone or skin as the only site of disease.
boolean
C0391978 (UMLS CUI [1])
C1123023 (UMLS CUI [2])