Caucasians Age
Item
caucasians ≥ 18 years of age
boolean
C0043157 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
ATRIAL FIBRILLATION SYMPTOMATIC Typical | Lone atrial fibrillation
Item
history of typical or lone symptomatic af
boolean
C0741283 (UMLS CUI [1,1])
C3538928 (UMLS CUI [1,2])
C0340489 (UMLS CUI [2])
Atrial Fibrillation Symptoms
Item
af symptoms present at least once per month
boolean
C0004238 (UMLS CUI [1,1])
C1457887 (UMLS CUI [1,2])
Electrocardiography Atrial Fibrillation | Randomization
Item
ecg that was recorded within 12 months of randomization showing af
boolean
C1623258 (UMLS CUI [1,1])
C0004238 (UMLS CUI [1,2])
C0034656 (UMLS CUI [2])
Class I antiarrhythmic drug | Class III antiarrhythmic drug
Item
starting a class i or class iii aad
boolean
C0360692 (UMLS CUI [1])
C0360703 (UMLS CUI [2])
Sinus rhythm
Item
in sinus rhythm at enrollment
boolean
C0232201 (UMLS CUI [1])
Ability Informed Consent
Item
able to give informed consent
boolean
C0085732 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
Permanent atrial fibrillation | Isolated Atrial Flutter
Item
permanent af or isolated atrial flutter.
boolean
C2586056 (UMLS CUI [1])
C0004239 (UMLS CUI [2,1])
C0205409 (UMLS CUI [2,2])
Cardiac Surgery procedures | Thoracic Surgical Procedures
Item
cardiac or thoracic surgery within the previous 6 months
boolean
C0018821 (UMLS CUI [1])
C0524832 (UMLS CUI [2])
Use of Amiodarone | Cardiac Arrhythmia | Hospitals
Item
previous use of amiodarone other than short-term use (e.g. for an acute arrhythmia in hospital)
boolean
C1524063 (UMLS CUI [1,1])
C0002598 (UMLS CUI [1,2])
C0003811 (UMLS CUI [2])
C0019994 (UMLS CUI [3])
Disease Probably Fatal
Item
medical condition that is likely to be fatal in less than one year
boolean
C0012634 (UMLS CUI [1,1])
C0750492 (UMLS CUI [1,2])
C1302234 (UMLS CUI [1,3])
Anti-Arrhythmia Agents Past
Item
received 2 or more aads in past
boolean
C0003195 (UMLS CUI [1,1])
C1444637 (UMLS CUI [1,2])
Creatinine clearance measurement
Item
creatinine clearance <40 ml/min
boolean
C0373595 (UMLS CUI [1])
Medical contraindication Class I antiarrhythmic drug | Structural disorder of heart | Myocardial Infarction
Item
contra-indication to a class i aad e.g., structural heart disease, or history of mi
boolean
C1301624 (UMLS CUI [1,1])
C0360692 (UMLS CUI [1,2])
C1290384 (UMLS CUI [2])
C0027051 (UMLS CUI [3])
Medical contraindication Class III antiarrhythmic drug | Congenital long QT syndrome | Acquired long QT syndrome | QTc
Item
contra-indication to a class iii aad, e.g., congenital or acquired long qt syndrome with qtc>450 ms at baseline
boolean
C1301624 (UMLS CUI [1,1])
C0360703 (UMLS CUI [1,2])
C1141890 (UMLS CUI [2])
C2732979 (UMLS CUI [3])
C0860814 (UMLS CUI [4])
Reversible cause Atrial Fibrillation | Thyrotoxicosis
Item
a reversible cause of af (e.g., thyrotoxicosis)
boolean
C0205343 (UMLS CUI [1,1])
C0015127 (UMLS CUI [1,2])
C0004238 (UMLS CUI [1,3])
C0040156 (UMLS CUI [2])
Prior Therapy Class I antiarrhythmic drug | Prior Therapy Class III antiarrhythmic drug
Item
previously treated with class i and class iii antiarrhythmic drugs
boolean
C1514463 (UMLS CUI [1,1])
C0360692 (UMLS CUI [1,2])
C1514463 (UMLS CUI [2,1])
C0360703 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
females who are pregnant or nursing.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Atrioventricular node Severe dysfunction | electronic pacemaker
Item
history of severe av node dysfunction unless an electronic pacemaker is present
boolean
C0004247 (UMLS CUI [1,1])
C3887504 (UMLS CUI [1,2])
C0205082 (UMLS CUI [1,3])
C0178611 (UMLS CUI [2])
Other Racial group | Caucasians
Item
any race other than caucasian
boolean
C0034510 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0043157 (UMLS CUI [2])
Study Subject Participation Status | Relative First degree | Relative Second degree
Item
first- or second-degree relative has already participated in the study.
boolean
C2348568 (UMLS CUI [1])
C0080103 (UMLS CUI [2,1])
C0444502 (UMLS CUI [2,2])
C0080103 (UMLS CUI [3,1])
C0443298 (UMLS CUI [3,2])