Disease characteristics
Item
-disease characteristics--
boolean
C1705348 (UMLS CUI [1])
Multiple sclerosis relapse
Item
diagnosis of multiple sclerosis relapsing-remitting defined as 2 exacerbations and a worsening of neurologic function over 1 day followed by at least 30 days of no progression or secondary-progressive defined as increase of at least 1.0 unit on expanded disability status scale (edss) in past 2 years with or without exacerbations
boolean
C0856120 (UMLS CUI [1])
C0581392 (UMLS CUI [2])
C0746866 (UMLS CUI [3])
C0451246 (UMLS CUI [4])
Therapy
Item
-prior/concurrent therapy--
boolean
C0087111 (UMLS CUI [1])
Biologic therapy
Item
biologic therapy: prior interferon beta 1a, 1b, or glatiramer acetate no concurrent interferon beta 1a, 1b, or glatiramer acetate
boolean
C0005527 (UMLS CUI [1])
Endocrine therapy
Item
endocrine therapy: concurrent oral and iv corticosteroids allowed
boolean
C0279025 (UMLS CUI [1])
Patient characteristics
Item
-patient characteristics--
boolean
C0815172 (UMLS CUI [1])
Edss
Item
performance status: edss no greater than 7.0
boolean
C0451246 (UMLS CUI [1])
Hematopoietic status
Item
hematopoietic: no hematologic dysfunction including hemolytic anemia
boolean
C1292123 (UMLS CUI [1])
Liver function
Item
hepatic: no hepatic dysfunction
boolean
C0232741 (UMLS CUI [1])
Renal function
Item
renal: no renal dysfunction
boolean
C0232804 (UMLS CUI [1])
Cardiovascular function
Item
cardiovascular: no cardiac pacemaker
boolean
C0678859 (UMLS CUI [1])
Comorbidity
Item
other: not pregnant or nursing negative pregnancy test no intracranial clips, metal implants, or external clips within 10 mm of head no metal in eyes no known gadolinium texaphyrin allergy no known claustrophobia
boolean
C0009488 (UMLS CUI [1])