Asthma | Chest symptom/complaint | Forced Expiratory Volume in 1 Second Reversibility | Inhaled albuterol preparation | Bronchial Hyperreactivity | Lung function testing normal | Methacholine
Item
1. confirmed asthma. diagnosis of asthma is made with episodic chest symptoms and a documented reversibility of at least 12% and/or 200 ml in fev1 after 200 ug of inhaled salbutamol or airway hyperresponsiveness in the case of normal lung function testing (pc20 methacholine < 4mg/ml) at the time of diagnosis.
boolean
C0004096 (UMLS CUI [1])
C0497258 (UMLS CUI [2])
C3830088 (UMLS CUI [3])
C0354688 (UMLS CUI [4])
C0085129 (UMLS CUI [5])
C0438186 (UMLS CUI [6])
C0600370 (UMLS CUI [7])
Age
Item
2. age between 18 and 80 years at study entry.
boolean
C0001779 (UMLS CUI [1])
Healthy Control | Never smoked tobacco | Spirometry normal | FEV1 | Forced vital capacity - finding
Item
3. healthy controls: never-smokers, normal spirometry (baseline fev1 > 85% predicted and fev1/fvc greater than 0.7).
boolean
C2986479 (UMLS CUI [1])
C0425293 (UMLS CUI [2])
C0855776 (UMLS CUI [3])
C0748133 (UMLS CUI [4])
C1287681 (UMLS CUI [5])
Exacerbation of asthma | Therapy change | Change in asthma management plan | Adrenal Cortex Hormones
Item
1. asthma exacerbation within the last 6 weeks, defined as worsening of asthma symptoms requiring a change in therapy by a physician or a change in regular asthma therapy (including short course of oral corticosteroids)
boolean
C0349790 (UMLS CUI [1])
C3665894 (UMLS CUI [2])
C1272202 (UMLS CUI [3])
C0001617 (UMLS CUI [4])
Lung diseases | Asthma
Item
2. any lung disease other than asthma.
boolean
C0024115 (UMLS CUI [1])
C0004096 (UMLS CUI [2])
Acute inflammatory disease | Common Cold
Item
3. acute inflammatory disease (e.g. common cold) within the last 4 weeks.
boolean
C1290885 (UMLS CUI [1])
C0009443 (UMLS CUI [2])
Intake Adrenal Cortex Hormones
Item
4. regular intake of oral steroids.
boolean
C1512806 (UMLS CUI [1,1])
C0001617 (UMLS CUI [1,2])
Smoking | Smoking History
Item
5. active smoking habits / positive history of smoking.
boolean
C0037369 (UMLS CUI [1])
C1519384 (UMLS CUI [2])
Liver diseases
Item
6. acute or chronic hepatic disease.
boolean
C0023895 (UMLS CUI [1])
Kidney Failure | Renal Replacement Therapy
Item
7. renal failure or renal replacement therapy.
boolean
C0035078 (UMLS CUI [1])
C0206074 (UMLS CUI [2])
Pregnancy
Item
8. pregnancy.
boolean
C0032961 (UMLS CUI [1])