asthma
Item
asthma is defined as a chronic inflammatory disorder, leading to recurrent episodes of wheezing, breathlessness, chest tightness, and/or coughing, based on variable airway obstruction [18]. children with docter-diagnosed asthma known at the department of paediatric pulmonology, were recruited from the university hospital maastricht. atopic and not atopic asthmatic children were allowed; treatment with inhalation corticosteroïd (ics) was not obliged.
boolean
C0004096 (UMLS CUI [1])
C0586793 (UMLS CUI [2])
cystic fibrosis
Item
children known with cf were recruited from university hospital maastricht. cf was defined as a combination of typical clinical features and an abnormal sweat test (chloride > 60 mm). cf lung disease was treated according to the cbo consensus ref. main aspects of treatment were:
boolean
C0010674 (UMLS CUI [1])
antibiotic treatment
Item
antibiotic treatment,
boolean
C0003232 (UMLS CUI [1])
agents to promote airway secretion clearance
Item
agents to promote airway secretion clearance, such as dnase,
boolean
C3804983 (UMLS CUI [1])
bronchodilator
Item
bronchodilators, and,
boolean
C0006280 (UMLS CUI [1])
physiotherapy
Item
physiotherapy. all alternations of medical therapy were allowed and accurately documented.
boolean
C0949766 (UMLS CUI [1])
comorbidity limiting study protocol
Item
diseases that may interfere with the results of the study (e.g. upper airway infection, cor vitium, anatomic abnormalities of the airway and other chronic inflammatory diseases, such as morbus crohn and rheumatoid arthritis),
boolean
C1321605 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
C0009488 (UMLS CUI [1,3])
mental retardation
Item
mental retardation,
boolean
C0025362 (UMLS CUI [1])
inability to perform measurements properly
Item
inability to perform measurements properly,
boolean
C1321605 (UMLS CUI [1])
active smoking
Item
active smoking and,
boolean
C3241966 (UMLS CUI [1])
papaverin, sodium nitroprusside, angiotensin-converting enzyme (ace) inhibitors, oxymetazoline, l-arginine, or nitric oxide synthase (nos) inhibitors
Item
use of the following medication: papaverin, sodium nitroprusside, angiotensin-converting enzyme (ace) inhibitors, oxymetazoline, l-arginine, or nitric oxide synthase (nos) inhibitors
boolean
C0030350 (UMLS CUI [1])
C0037533 (UMLS CUI [2])
C0003015 (UMLS CUI [3])
C0030071 (UMLS CUI [4])
C0003765 (UMLS CUI [5])
C1373060 (UMLS CUI [6])