Anti-hcv antibody test
Item
positive anti-hcv antibody test
boolean
C0201487 (UMLS CUI [1])
Response to standard HCV treatment (by HCV RNA)
Item
patients who did not respond to treatment with standard interferon + ribavirin (hcv rna+ by pcr in the last month of treatment)
boolean
C0521982 (UMLS CUI [1,1])
C0717864 (UMLS CUI [1,2])
C0369335 (UMLS CUI [2])
Liver function
Item
compensated liver disease
boolean
C0232741 (UMLS CUI [1])
Neutrophil count
Item
neutrophil count over or equal to1000/mm3
boolean
C0200633 (UMLS CUI [1])
Platelet count
Item
platelet count over or equal to 100 giga/l
boolean
C0032181 (UMLS CUI [1])
Haemoglobin
Item
haemoglobin over or equal to 10g/dl
boolean
C0518015 (UMLS CUI [1])
Post-treatment liver biopsy (metavir histological score + fibrosis score)
Item
patients had to have undergone a post-treatment liver biopsy within a year, showing a metavir histological score over or equal to a1f1, without cirrhosis (fibrosis score below f4)
boolean
C0193388 (UMLS CUI [1,1])
C2709088 (UMLS CUI [1,2])
C3888527 (UMLS CUI [2])
C1954437 (UMLS CUI [3])
ALT measurement and HCV RNA
Item
alt over n and hcv rna+ at screening
boolean
C0201836 (UMLS CUI [1])
C0369335 (UMLS CUI [2])
Co-infections
Item
co-infection with hepatitis b or human immunodeficiency virus
boolean
C2242656 (UMLS CUI [1])
C0275524 (UMLS CUI [2,1])
C0019682 (UMLS CUI [2,2])
Liver disease etiology
Item
any other cause of liver disease
boolean
C0023895 (UMLS CUI [1,1])
C1314792 (UMLS CUI [1,2])
Substance use disorder
Item
active drug abuse, active alcohol consumption above 40g/day
boolean
C0038586 (UMLS CUI [1])
Organ graft
Item
organ grafts
boolean
C0524930 (UMLS CUI [1])
Hepatocellular carcinoma
Item
presence of hepatocellular carcinoma
boolean
C2239176 (UMLS CUI [1])
Comorbidity
Item
cardiovascular, metabolic, renal, haematological, neurological or psychiatric disease
boolean
C0009488 (UMLS CUI [1])
Amantadine
Item
patients with previous amantadine use
boolean
C0002403 (UMLS CUI [1])
Immunossuppressive or antiviral treatment and drug intolerance
Item
systemic immunosuppressive or antiviral treatment during the last 24 weeks and those with a history of interferon and/or ribavirin intolerance
boolean
C0021079 (UMLS CUI [1])
C2363964 (UMLS CUI [2])
C0277585 (UMLS CUI [3])