AML
Item
newly diagnosed aml based on who classification
boolean
C0023467 (UMLS CUI [1])
Age, chemotherapy
Item
age 70 years or older for whom the treatment of choice is low-intensity therapy by investigator assessment or who has refused intensive induction therapy recommended by investigator
boolean
C0001779 (UMLS CUI [1])
C0392920 (UMLS CUI [2])
ECOG
Item
ecog performance status 0-2
boolean
C1520224 (UMLS CUI [1])
renal function
Item
adequate renal function
boolean
C0232804 (UMLS CUI [1])
liver function
Item
adequate liver function
boolean
C0232741 (UMLS CUI [1])
ability to swallow capsules
Item
able to swallow capsules
boolean
C0006935 (UMLS CUI [1,1])
C0085732 (UMLS CUI [1,2])
contraception
Item
agree to practice effective contraception
boolean
C0700589 (UMLS CUI [1])
informed consent form
Item
ability to understand and willingness to sign the informed consent form
boolean
C0021430 (UMLS CUI [1])
APL or extramedullary tumor without bone marrow involvement
Item
aml is of the sub-type of acute promyelocytic leukemia or extramedullary myeloid tumor without bone marrow involvement
boolean
C0023487 (UMLS CUI [1])
C1517677 (UMLS CUI [2])
C1868812 (UMLS CUI [3])
anti-cancer therapy
Item
having received any systemic anti-cancer therapy for aml or received treatment with hypomethylating agents or cytotoxic chemotherapy for the preceding mds or mpd
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
C1531518 (UMLS CUI [3])
cns leukemia
Item
known or suspected central nervous system (cns) involvement by leukemia
boolean
C1332884 (UMLS CUI [1])
comorbidity
Item
uncontrolled intercurrent illness
boolean
C0009488 (UMLS CUI [1])
hypersensitivity to decitabine
Item
known hypersensitivity to decitabine
boolean
C0020517 (UMLS CUI [1,1])
C0049065 (UMLS CUI [1,2])
hiv
Item
known to be hiv-positive
boolean
C0019682 (UMLS CUI [1])