chronic lymphocytic leukemia
Item
confirmed diagnosis of b-cell chronic lymphocytic leukemia
boolean
C0023434 (UMLS CUI [1])
rai stage
Item
rai stage 0-ii (binet stage a) disease
boolean
C1514715 (UMLS CUI [1])
ID.3
Item
meets 1 of the following criteria:
boolean
ID.4
Item
high-risk disease, as defined by the following:
boolean
thymidine kinase
Item
serum thymidine kinase level > 7.0 u/l
boolean
C0040078 (UMLS CUI [1])
β2-microglobulin
Item
elevated β2-microglobulin level
boolean
C0005149 (UMLS CUI [1])
non-nodular bone marrow infiltration
Item
presence of non-nodular bone marrow infiltration
boolean
C0445127 (UMLS CUI [1,1])
C0332448 (UMLS CUI [1,2])
C0005953 (UMLS CUI [2])
ID.8
Item
short lymphocyte doubling time
boolean
ID.9
Item
low-risk disease
boolean
ID.10
Item
meets none of the criteria (as listed above) for high-risk disease
boolean
life expectancy
Item
life expectancy: more than 6 months
boolean
C0023671 (UMLS CUI [1])
autoimmune hemolytic anemia
Item
no autoimmune hemolytic anemia
boolean
C0002880 (UMLS CUI [1])
thrombocytopenia
Item
no thrombocytopenia
boolean
C0040034 (UMLS CUI [1])
severe organ dysfunction
Item
no severe organ dysfunction
boolean
C0009488 (UMLS CUI [1])
malignancies
Item
no other prior or concurrent malignancy
boolean
C0006826 (UMLS CUI [1])
chemotherapy
Item
no prior chemotherapy
boolean
C3665472 (UMLS CUI [1])
concurrent chemotherapy
Item
no other concurrent chemotherapy
boolean
C3665472 (UMLS CUI [1])