age
Item
40 patients between the ages of 50 and 75 yrs undergoing unilateral total knee replacement for non-inflammatory degenerative osteoarthritis will participate, as well as 10 control participants will be recruited from the general population for the present study matching to experimental groups for age, gender and bmi.patients who do not meet any exclusion criteria.
boolean
C0001779 (UMLS CUI [1])
Degenerative polyarthritis Joints Lower Extremity
Item
potential participants for the control group will be asked if they have had degenerative osteoarthritis of lower-limb joints (hip, knee and ankle) and if they have they will be excluded.
boolean
C0029408 (UMLS CUI [1,1])
C0022417 (UMLS CUI [1,2])
C0023216 (UMLS CUI [1,3])
exclusion
Item
exclusion for patient group
boolean
C2828389 (UMLS CUI [1])
total knee arthroplasty; Joints Lower Extremity
Item
1. patients suffering from any other lower-limb joint disorders other than the one for which total knee arthroplasty.
boolean
C0086511 (UMLS CUI [1])
C0022417 (UMLS CUI [2,1])
C0023216 (UMLS CUI [2,2])
Joint replacement of lower extremity
Item
2. patients with any other joint replacement in the ipsilateral and contralateral limb.
boolean
C0177563 (UMLS CUI [1])
active infection
Item
3. patients with evidence of active infection.
boolean
C0009450 (UMLS CUI [1])
comorbidity; Neurodegenerative Disorders; musculoskeletal disease
Item
4. patients with neurologic or musculoskeletal disease that may adversely affect gait, weight-bearing or quadriceps function.
boolean
C0009488 (UMLS CUI [1])
C0524851 (UMLS CUI [2])
C0026857 (UMLS CUI [3])
neuropathic joints
Item
5. patients with neuropathic joints.
boolean
C0149739 (UMLS CUI [1])
bone grafts
Item
6. patients requiring structural bone grafts.
boolean
C0005976 (UMLS CUI [1])
hypersensitivity; Cobalt-Chromium-Molybdenum Alloy
Item
7. patients with a documented allergy to cobalt chromium molybdenum.
boolean
C0020517 (UMLS CUI [1])
C0205998 (UMLS CUI [2])
bmi
Item
8. patient with a bmi larger than 30 kg/m2.
boolean
C1305855 (UMLS CUI [1])