schizophrenia or schizoaffective disorder
Item
patients: meets dsm-iv criteria for schizophrenia, any type, or schizoaffective disorder;
boolean
C0036341 (UMLS CUI [1])
C0036337 (UMLS CUI [2])
age
Item
aged 18 to 60 years;
boolean
C0001779 (UMLS CUI [1])
informed consent
Item
able to give informed consent;
boolean
C0021430 (UMLS CUI [1])
medication
Item
no medication changes for 2 weeks prior to and during the period of study;
boolean
C0013227 (UMLS CUI [1])
antipsychotic agents
Item
patients: currently taking an antipsychotic.
boolean
C0040615 (UMLS CUI [1])
psychiatric disorder
Item
controls: axis i psychiatric disorder criteria met except for substance use disorders as below;
boolean
C0004936 (UMLS CUI [1])
substance abuse
Item
meets dsm-iv criteria for the diagnoses of substance abuse or dependence within the past six months;
boolean
C0038586 (UMLS CUI [1])
legal status
Item
involuntary legal status (as per missouri law);
boolean
C0580275 (UMLS CUI [1])
comorbidity
Item
the presence of any serious medical disorder that may (as confirmed by peer-reviewed literature) confound the assessment of symptoms, relevant biologic measures or diagnosis;
boolean
C0009488 (UMLS CUI [1])
diabetes mellitus
Item
insulin- or non-insulin-dependent diabetes mellitus;
boolean
C0011849 (UMLS CUI [1])
surgery
Item
any intra-abdominal or intrathoracic surgery or limb amputation within the prior 6 months;
boolean
C0543467 (UMLS CUI [1])
heart diseases
Item
any diagnosed cardiac condition causing documented hemodynamic compromise;
boolean
C0018799 (UMLS CUI [1])
respiratory disease
Item
any diagnosed respiratory condition causing documented or clinically recognized hypoxia;
boolean
C0035204 (UMLS CUI [1])
pregnancy, medication, comorbidity
Item
pregnancy or high dose estrogens, fever, narcotic therapy, acute sedative hypnotic withdrawal, corticosteroid or spironolactone therapy, dehydration, epilepsy, endocrine disease, high-dose benzodiazepine therapy (> 25 mg/day of diazepam), or any medical condition known to interfere with glucose utilization;
boolean
C0032961 (UMLS CUI [1])
C0013227 (UMLS CUI [2])
C0009488 (UMLS CUI [3])
mental retardation
Item
meets dsm-iv criteria for mental retardation (mild or worse).
boolean
C0025362 (UMLS CUI [1])