down syndrome
Item
presence of clinically determined down syndrome (karyotypes optional)
boolean
C0013080 (UMLS CUI [1])
consent
Item
appropriately signed and witnessed consent form
boolean
C0021430 (UMLS CUI [1])
age
Item
age of 50 years or older at the start of the protocol
boolean
C0001779 (UMLS CUI [1])
Medical status
Item
medically stable
boolean
C3899485 (UMLS CUI [1])
Medication status
Item
medications stable more than 1 month
boolean
C0013227 (UMLS CUI [1,1])
C1547775 (UMLS CUI [1,2])
caregiver
Item
involvement/cooperation of informant/caregiver
boolean
C0085537 (UMLS CUI [1])
medical/neurological condition associated with dementia
Item
medical/neurological condition (other than alzheimer disease) associated with dementia
boolean
C0027765 (UMLS CUI [1,1])
C0497327 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
C0002395 (UMLS CUI [1,4])
C0012634 (UMLS CUI [2,1])
C0497327 (UMLS CUI [2,2])
C0439801 (UMLS CUI [2,3])
C0002395 (UMLS CUI [2,4])
brief praxis test
Item
inability to adequately perform the brief praxis test, as demonstrated by a score <20
boolean
C0009240 (UMLS CUI [1,1])
C0746940 (UMLS CUI [1,2])
C0039593 (UMLS CUI [1,3])
hachinski score
Item
in the presence of dementia, modified hachinski score > 4 at screening visit
boolean
C0475492 (UMLS CUI [1])
major depression
Item
major depression within 3 months
boolean
C1269683 (UMLS CUI [1])
coagulopathy
Item
history of coagulopathy (inherited or acquired)
boolean
C0005779 (UMLS CUI [1])
anticoagulants
Item
current use of anticoagulants
boolean
C0003280 (UMLS CUI [1])
experimental medications
Item
use of experimental medications within 2 months
boolean
C0304229 (UMLS CUI [1])
vitamin e
Item
regular use of vitamin e greater than 50 units per day during the previous 6 months
boolean
C1142098 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
allergy
Item
allergy to vitamin e
boolean
C002051 (UMLS CUI [1,1])
C0042874 (UMLS CUI [1,2])