AML
Item
newly diagnosed adult patients = 65 years old with a cytopathologically confirmed diagnosis of high-risk aml
boolean
C0023467 (UMLS CUI [1])
bone marrow blasts
Item
= 20% bone marrow blasts via bone marrow aspiration or biopsy
boolean
C0368761 (UMLS CUI [1])
prior treatment for aml
Item
the patient has not yet been treated for aml
boolean
C0087111 (UMLS CUI [1])
high-risk category
Item
1º or 2º aml patients with high-risk category features
boolean
C0086930 (UMLS CUI [1])
ECOG
Item
ecog ps = 2
boolean
C1520224 (UMLS CUI [1])
renal and hepatic function
Item
renal function and liver function limits.
boolean
C0232804 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
cytogenetic profile
Item
patient with a 'favorable' or 'better-risk' cytogenetic profile = t(15;17); t(8;21); or inv(16) or t(16;16)
boolean
C0010802 (UMLS CUI [1])
cns leukemia
Item
patient has clinical symptoms suggestive of cns leukemia and/or csf findings for cns leukemia
boolean
C1332884 (UMLS CUI [1])
deacetylase inhibitors
Item
prior treatment with deacetylase inhibitors (daci) including, panobinostat
boolean
C1333261 (UMLS CUI [1])
cardiac function
Item
impaired cardiac function
boolean
C0232164 (UMLS CUI [1])
pregnancy or lactation
Item
female patient who is pregnant or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
contraception
Item
male patient who is not willing to use a barrier method of contraception
boolean
C0700589 (UMLS CUI [1])