CLL
Item
patients with chronic lymphocytic leukemia, meeting 1 of the following criteria:
boolean
C0023434 (UMLS CUI [1])
binet stage
Item
binet stage b or c disease
boolean
C1511118 (UMLS CUI [1])
binet stage a disease and at high risk for disease progression
Item
binet stage a disease and at high risk for disease progression, defined as the following:
boolean
C1511118 (UMLS CUI [1])
non-nodular marrow infiltration or lymphocyte doubling time < 12 months
Item
non-nodular marrow infiltration or lymphocyte doubling time < 12 months
boolean
C3854434 (UMLS CUI [1])
C2986483 (UMLS CUI [2])
thymidine kinase, ß-2-microglobulin
Item
thymidine kinase > 7.0 u/l or ß-2-microglobulin > 3.5 mg/l
boolean
C0040078 (UMLS CUI [1])
C0005149 (UMLS CUI [2])
polymerase chain reaction-amplifiable clonal cdriii rearrangement of the igv_h
Item
polymerase chain reaction-amplifiable clonal cdriii rearrangement of the igv_h
boolean
C0887928 (UMLS CUI [1])
ecog performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
no concurrent disease resulting in major organ dysfunction
Item
no concurrent disease resulting in major organ dysfunction
boolean
C0009488 (UMLS CUI [1])
no prior combination therapy comprising melphalan, dexamethasone, carmustine, cytarabine, and etoposide (dexa-beam)
Item
no prior combination therapy comprising melphalan, dexamethasone, carmustine, cytarabine, and etoposide (dexa-beam)
boolean
C0025241 (UMLS CUI [1])
C0011777 (UMLS CUI [2])
C0007257 (UMLS CUI [3])
C0010711 (UMLS CUI [4])
C0015133 (UMLS CUI [5])
no more than 1 prior chemotherapy regimen
Item
no more than 1 prior chemotherapy regimen
boolean
C0392920 (UMLS CUI [1])
no prior chemotherapy regimen longer than 6 months in duration
Item
no prior chemotherapy regimen longer than 6 months in duration
boolean
C0392920 (UMLS CUI [1])