age
Item
age: 16 and over
boolean
C0001779 (UMLS CUI [1])
performance status
Item
performance status: calgb 0-2 karnofsky 70-100%
boolean
C1520224 (UMLS CUI [1])
life expectancy
Item
life expectancy: more than 2 months
boolean
C0023671 (UMLS CUI [1])
hematopoietic
Item
hematopoietic: neutrophil count at least 1,500/mm3 platelet count at least 100,000/mm3
boolean
C0200633 (UMLS CUI [1])
C0005821 (UMLS CUI [2])
hepatic function
Item
hepatic: bilirubin less than 3 times normal sgot and sgpt less than 3 times normal alkaline phosphatase less than 3 times normal hepatitis b surface antigen negative
boolean
C1278039 (UMLS CUI [1])
C0004002 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C1561546 (UMLS CUI [4])
C0019168 (UMLS CUI [5])
renal function
Item
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
cardiac function
Item
cardiovascular: cardiac ejection fraction normal by muga scan no uncontrolled or severe cardiovascular disease, including the following: myocardial infarction within the past 6 months congestive heart failure symptomatic angina (despite optimal medical management) life-threatening arrhythmia or hypertension
boolean
C0232174 (UMLS CUI [1])
C0007222 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
C0007222 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0027051 (UMLS CUI [4])
C0018802 (UMLS CUI [5])
C0002962 (UMLS CUI [6])
C0003811 (UMLS CUI [7,1])
C2826244 (UMLS CUI [7,2])
C0020538 (UMLS CUI [8,1])
C2826244 (UMLS CUI [8,2])
pulmonary function
Item
pulmonary: pulmonary function tests (dlco and spirometry) greater than 60% predicted
boolean
C0024119 (UMLS CUI [1])
other comorbidities
Item
other: hiv negative no serious organ dysfunction (unless caused by lymphoma) no active bacterial, viral, or fungal infection no active peptic ulcer disease no uncontrolled diabetes mellitus no other malignancy except curatively treated carcinoma in situ of the cervix or basal cell or squamous cell skin cancer no other serious medical or psychiatric illness that would preclude study
boolean
C0019682 (UMLS CUI [1])
C0349410 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C0009450 (UMLS CUI [3])
C0030920 (UMLS CUI [4])
C0011849 (UMLS CUI [5,1])
C0205318 (UMLS CUI [5,2])
C0006826 (UMLS CUI [6])
C1321605 (UMLS CUI [7,1])
C0439801 (UMLS CUI [7,2])
C0009488 (UMLS CUI [7,3])
pregnancy
Item
not pregnant
boolean
C0032961 (UMLS CUI [1])
prior chemotherapy
Item
chemotherapy: see disease characteristics prior nitrosourea allowed if cumulative dose no more than 600 mg/m2 prior bleomycin allowed if cumulative dose no more than 300 units/m2 prior doxorubicin allowed if cumulative dose no more than 450 mg/m2 no prior high-dose etoposide (more than 1,800 mg/m2) no prior high-dose cyclophosphamide (more than 100 mg/kg) no chemotherapy within 4 weeks (no melphalan, nitrosourea, or mitomycin within 6 weeks) prior to bone marrow collection
boolean
C0028210 (UMLS CUI [1])
C0005740 (UMLS CUI [2])
C0013089 (UMLS CUI [3])
C0384397 (UMLS CUI [4])
C0010583 (UMLS CUI [5])
prior radiotherapy
Item
no prior salvage therapy radiotherapy: see disease characteristics no prior radiotherapy to liver or lung prior other radiotherapy allowed if doses do not exceed the following limits: 1,400 cgy to the mediastinum 1,400 cgy to the whole abdomen 4,000 cgy to the cns
boolean
C0085405 (UMLS CUI [1])
C1522449 (UMLS CUI [2])