all
Item
acute lymphoblastic leukemia
boolean
C0023449 (UMLS CUI [1])
lymphoblastic lymphoma
Item
patients with lymphoblastic lymphoma are also eligible
boolean
C0278721 (UMLS CUI [1])
untreated ALL
Item
no prior anti-leukemic therapy except <1 week of steroids, and/or emergent radiation therapy to the mediastinum, or hydroxyurea or emergent leukopheresis. longer steroid use for diseases other than leukemia is permitted.
boolean
C0279088 (UMLS CUI [1])
age
Item
age 51-75 years
boolean
C0001779 (UMLS CUI [1])
ejection fraction
Item
ejection fraction > 45 percent
boolean
C0232174 (UMLS CUI [1])
creatinine
Item
creatinine < 2.0 mg/dl
boolean
C0201976 (UMLS CUI [1])
total bilirubin
Item
total bilirubin < 3.0 mg/dl
boolean
C0201913 (UMLS CUI [1])
ecog performance status
Item
ecog performance status of 0, 1, 2
boolean
C1520224 (UMLS CUI [1])
pregnant or breastfeeding
Item
non-pregnant and non lactating
boolean
C0549206 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
b-cell leukemia
Item
known mature b-cell all by the presence of any of the following: surface immunoglobulin, l3 morphology, t(8;14)(q24;q32), t(8;22), or t(2;8)
text
C0279593 (UMLS CUI [1])
HIV positivity
Item
known hiv positive
boolean
C0019699 (UMLS CUI [1])
comorbid medical condition, in the investigator's opinion, would make participation in this trial and adherence to the protocol guidelines difficult
Item
comorbid medical condition, in the investigator's opinion, would make participation in this trial and adherence to the protocol guidelines difficult
boolean
C1321605 (UMLS CUI [1])
C0439801 (UMLS CUI [2])
C0009488 (UMLS CUI [3])
active psychiatric or mental illness making informed consent or careful clinical follow-up unlikely
Item
active psychiatric or mental illness making informed consent or careful clinical follow-up unlikely
boolean
C0021430 (UMLS CUI [1])
C0439801 (UMLS CUI [2])
C0009488 (UMLS CUI [3])