pathologically documented acute lymphoblastic leukemia
Item
patients must have pathologically documented acute lymphoblastic leukemia, excluding mature b-cell all.
boolean
C0023449 (UMLS CUI [1])
no prior therapy for leukemia
Item
no prior therapy for leukemia with the following exceptions
boolean
C0279088 (UMLS CUI [1])
steroid therapy
Item
up to one week of steroids;
boolean
C0149783 (UMLS CUI [1])
leukapheresis
Item
emergent leukapheresis;
boolean
C0023416 (UMLS CUI [1])
emergency treatment with hydroxyurea
Item
emergency treatment for hyperleukocytosis with hydroxyurea;
boolean
C0020402 (UMLS CUI [1])
cranial rt for cns leukostasis
Item
cranial rt for cns leukostasis (one dose only);
boolean
C0205918 (UMLS CUI [1])
C3163632 (UMLS CUI [2])
emergent radiation therapy to the mediastinum.
Item
emergent radiation therapy to the mediastinum.
boolean
C0205918 (UMLS CUI [1])
C0025063 (UMLS CUI [2])
Ecog performance status
Item
eastern cooperative oncology group (ecog) performance status 0 to 2.
boolean
C1520224 (UMLS CUI [1])
Age
Item
between the ages of 18 to 50 years.
boolean
C0001779 (UMLS CUI [1])
infection
Item
uncontrolled active infection.
boolean
C0009450 (UMLS CUI [1])
pregnant or breastfeeding
Item
pregnant or breastfeeding
boolean
C0549206 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
pancreatitis
Item
prior history of pancreatitis.
boolean
C0030305 (UMLS CUI [1])
prior history of a cerebrovascular accident or hemorrhage
Item
prior history of a cerebrovascular accident or hemorrhage
boolean
C0038454 (UMLS CUI [1])
C2937358 (UMLS CUI [2])
hiv infection
Item
evidence of infection with the human immunodeficiency virus.
boolean
C0019693 (UMLS CUI [1])
active psychiatric or mental illness
Item
active psychiatric or mental illness making informed consent or careful clinical follow-up unlikely.
boolean
C0021430 (UMLS CUI [1])
C0439801 (UMLS CUI [2])
C0009488 (UMLS CUI [3])
other
Item
the treating physician should consider all relevant medical and other considerations when deciding whether this protocol is appropriate for a particular patient.
boolean
C0205394 (UMLS CUI [1])
C0009488 (UMLS CUI [2])
C1321605 (UMLS CUI [3])