Age
Item
age 6 months - 25 years.
boolean
C0001779 (UMLS CUI [1])
diagnoses of acute leukemia
Item
diagnoses of acute leukemia (aml, all, biphenotypic leukemia), pre-leukemic syndromes (monosomy 7 or other bone marrow clonal malformations), jmml, myelodysplastic syndromes or cml.
boolean
C0023418 (UMLS CUI [1])
undergoing an allogeneic transplant as standard care
Item
undergoing an allogeneic transplant as standard care.
boolean
C0149615 (UMLS CUI [1])
performance status
Item
performance status: karnofsky/lansky>60%.
boolean
C0206065 (UMLS CUI [1])
chimerism testing
Item
availability of pre-transplant recipient's dna and donor's dna for chimerism testing. this could be dna or material from which dna could be extracted. frozen blood would be preferred. for some patients, post transplant specimens that are not infiltrated with donor cells may be used.
boolean
C3250865 (UMLS CUI [1])
bone marrow or pbmtc as stem cell source.hla matching: donor and recipient should be matched at a minimum of 7/8 antigens (a,b,c and drb1) for bone marrow and pbmtc transplants
Item
bone marrow or pbmtc as stem cell source.hla matching: donor and recipient should be matched at a minimum of 7/8 antigens (a,b,c and drb1) for bone marrow and pbmtc transplants.
boolean
C0005953 (UMLS CUI [1])
C0038250 (UMLS CUI [2])
no history of ≥grade iii acute gvhd
Item
no history of ≥grade iii acute gvhd.
boolean
C0856825 (UMLS CUI [1])
study subject participation status
Item
treatment on other experimental protocols, if withdrawal of immunosuppression interferes with procedures of follow-up on the primary study.
boolean
C2348568 (UMLS CUI [1])
leukemia relapse
Item
leukemia relapse defined as > 5 percent blasts on bone marrow exam or >1 percent leukemia cells by immunoflow mrd, or presence of extramedullary leukemia.
boolean
C0920028 (UMLS CUI [1])
acute gvhd
Item
history of acute gvhd ≥ stage iii or with any degree of active acute or cgvhd.
boolean
C0856825 (UMLS CUI [1])
steroid treatment
Item
on steroids for any reason.
boolean
C0149783 (UMLS CUI [1])
any condition that compromises compliance with the objectives and procedures of this protocol, as judged by the principal investigator.
Item
any condition that compromises compliance with the objectives and procedures of this protocol, as judged by the principal investigator.
boolean
C1321605 (UMLS CUI [1])
C0439801 (UMLS CUI [2])
C0009488 (UMLS CUI [3])
cells for dli cannot be obtained from the donor
Item
cells for dli cannot be obtained from the donor.
boolean
C1142167 (UMLS CUI [1])