Unstable angina
Item
Presenting or admitted to hospital with symptoms suspected to represent UA
boolean
C0002965 (UMLS CUI-1)
NSTEMI
Item
Presenting or admitted to hospital with symptoms suspected to represent NSTEMI
boolean
C3537184 (UMLS CUI-1)
Coronary angiography
Item
Planned coronary angiography, with PCI if indicated, within 72 hours of enrollment where possible.
boolean
C0085532 (UMLS CUI-1)
PCI
Item
Planned coronary angiography, with PCI if indicated, within 72 hours of enrollment where possible.
boolean
C1532338 (UMLS CUI-1)
Age
Item
Age greater than or equal to 60 years
boolean
C0001779 (UMLS CUI-1)
Troponin T
Item
Troponin T above the upper limit of normal for the local institution;
boolean
C1141947 (UMLS CUI-1)
Troponin I
Item
Troponin I above the upper limit of normal for the local institution;
boolean
C0920210 (UMLS CUI-1)
CK-MB
Item
CK-MB above the upper limit of normal for the local institution;
boolean
C0523584 (UMLS CUI-1)
ST depression
Item
Electrocardiogram (ECG) changes compatible with ischemia, i.e., ST depression at least 1 mm in 2 contiguous leads
boolean
C0520887 (UMLS CUI-1)
T wave inversion
Item
Electrocardiogram (ECG) changes compatible with ischemia, i.e., T wave inversion > 3 mm
boolean
C0520888 (UMLS CUI-1)
ST elevation
Item
Electrocardiogram (ECG) changes compatible with ischemia, i.e., or any dynamic ST shift or transient ST elevation
boolean
C0520886 (UMLS CUI-1)
Informed consent
Item
Written informed consent dated and signed
boolean
C0021430 (UMLS CUI-1)
Age
Item
Age < 21 years
boolean
C0001779 (UMLS CUI-1)
Heparin contraindicated
Item
Any contraindication to UFH
boolean
C2825026 (UMLS CUI-1)
C0522473 (UMLS CUI-2)
Fondaparinux contraindicated
Item
Any contraindication to fondaparinux
boolean
C1098510 (UMLS CUI-1)
C0522473 (UMLS CUI-2)
PCI contraindicated
Item
Contraindication for angiography or PCI at baseline
boolean
C1532338 (UMLS CUI-1)
C0522473 (UMLS CUI-2)
Angiography contraindicated
Item
Contraindication for angiography at baseline
boolean
C0085532 (UMLS CUI-1)
C0522473 (UMLS CUI-2)
Angina pectoris
Item
refractory or recurrent angina associated with dynamic ST-deviation
boolean
C0002962 (UMLS CUI-1)
Heart failure
Item
heart failure
boolean
C0018801 (UMLS CUI-1)
Ventricular arrhythmia
Item
life-threatening arrhythmias
boolean
C0085612 (UMLS CUI-1)
Hemodynamic instability
Item
hemodynamic instability
boolean
C0948268 (UMLS CUI-1)
Enoxaparin
Item
Subjects already receiving treatment with enoxaparin for treatment of the qualifying events
boolean
C0206460 (UMLS CUI-1)
LMWH
Item
Subjects already receiving treatment with LMWH for treatment of the qualifying events
boolean
C3536766 (UMLS CUI-1)
Bivalirudin
Item
Subjects already receiving treatment with bivalirudin for treatment of the qualifying events
boolean
C0168273 (UMLS CUI-1)
Unfractionated heparin
Item
Subjects already receiving treatment with UFH for treatment of the qualifying events
boolean
C2825026 (UMLS CUI-1)
History of stroke
Item
Hemorrhagic stroke within the last 12 months.
boolean
C0559159 (UMLS CUI-1)
Anticoagulation therapy
Item
Indication for anti-coagulation other than acute coronary syndrome (ACS) during the index hospitalization.
boolean
C0003281 (UMLS CUI-1)
Pregnancy
Item
Pregnancy or women of childbearing potential who are not using an effective method of contraception.
boolean
C0549206 (UMLS CUI-1)
Terminal illness
Item
Co-morbid condition with life expectancy less than 6 months.
boolean
C0679247 (UMLS CUI-1)
Experimental drug
Item
Currently receiving an experimental pharmacological agent.
boolean
C0304229 (UMLS CUI-1)
Myocardial Revascularization
Item
Revascularization procedure already performed for the qualifying event.
boolean
C0027056 (UMLS CUI-1)
Renal failure
Item
Severe renal insufficiency (i.e., estimated creatinine clearance <20 ml/min)
boolean
C1533077 (UMLS CUI-1)