Informed Consent
Item
1. written informed consent
boolean
C0021430 (UMLS CUI [1])
B-Cell Lymphoma Subtype
Item
2. histologically confirmed b-cell lymphoma of the following subtypes:
boolean
C0079731 (UMLS CUI [1,1])
C0449560 (UMLS CUI [1,2])
Diffuse Large B-Cell Lymphoma
Item
lbcdl
boolean
C0079744 (UMLS CUI [1])
Follicular Lymphoma Ann Arbor lymphoma staging system
Item
grade 3b follicular lymphoma
boolean
C0024301 (UMLS CUI [1,1])
C0432516 (UMLS CUI [1,2])
Mantle-cell lymphoma
Item
mantle-cell lymphoma
boolean
C0334634 (UMLS CUI [1])
B-Cell Lymphoma Transformation
Item
transformed b-cell lymphoma
boolean
C0079731 (UMLS CUI [1,1])
C1536010 (UMLS CUI [1,2])
Burkitt Lymphoma | Patient Inappropriate Allogeneic Transplantation
Item
burkitt lymphoma in patients not eligible for a conventional allogeneic transplant
boolean
C0006413 (UMLS CUI [1])
C0030705 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
C0040739 (UMLS CUI [2,3])
B-Cell Lymphoma CD20 positive High risk of
Item
3. high-risk b-cell cd20+ lymphoma defined by
boolean
C0079731 (UMLS CUI [1,1])
C0882818 (UMLS CUI [1,2])
C0332167 (UMLS CUI [1,3])
Chemotherapy cycle Quantity | Partial response Less Than
Item
having attained less than pr after two chemotherapy lines
boolean
C1302181 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C1521726 (UMLS CUI [2,1])
C0439092 (UMLS CUI [2,2])
Recurrent disease Post Transplantation
Item
post-transplantation relapse
boolean
C0277556 (UMLS CUI [1,1])
C0687676 (UMLS CUI [1,2])
C0040732 (UMLS CUI [1,3])
Disease detection PET/CT Before Autologous Transplantation | Disease detection CT Before Autologous Transplantation | Disease detection PET Before Autologous Transplantation | Disease detection PET/CT Post Autologous Transplantation | Disease detection CT Post Autologous Transplantation | Disease detection PET Post Autologous Transplantation
Item
presence of disease detected through a metabolic approach (pet/ct or else ct+pet) either before or after autologous transplantation
boolean
C0683509 (UMLS CUI [1,1])
C1699633 (UMLS CUI [1,2])
C0332152 (UMLS CUI [1,3])
C0040736 (UMLS CUI [1,4])
C0683509 (UMLS CUI [2,1])
C0040405 (UMLS CUI [2,2])
C0332152 (UMLS CUI [2,3])
C0040736 (UMLS CUI [2,4])
C0683509 (UMLS CUI [3,1])
C0032743 (UMLS CUI [3,2])
C0332152 (UMLS CUI [3,3])
C0040736 (UMLS CUI [3,4])
C0683509 (UMLS CUI [4,1])
C1699633 (UMLS CUI [4,2])
C0687676 (UMLS CUI [4,3])
C0040736 (UMLS CUI [4,4])
C0683509 (UMLS CUI [5,1])
C0040405 (UMLS CUI [5,2])
C0687676 (UMLS CUI [5,3])
C0040736 (UMLS CUI [5,4])
C0683509 (UMLS CUI [6,1])
C0032743 (UMLS CUI [6,2])
C0687676 (UMLS CUI [6,3])
C0040736 (UMLS CUI [6,4])
Transplantation, Autologous | Stem cell Collection Unable
Item
inability to collect enough stem cells for autologous transplantation
boolean
C0040736 (UMLS CUI [1])
C0038250 (UMLS CUI [2,1])
C1516698 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
Stable Disease
Item
4. stable disease at the time of transplantation
boolean
C0677946 (UMLS CUI [1])
Age
Item
5. age between 18 and 65
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
6. performance status (ecog) ≤ 2
boolean
C1520224 (UMLS CUI [1])
Pulmonary function | Carbon Monoxide Diffusing Capability Test
Item
7. normal and suitable pulmonary function (dlco ≥ 30%)
boolean
C0231921 (UMLS CUI [1])
C1516251 (UMLS CUI [2])
Left ventricular ejection fraction Ventriculography | Left ventricular ejection fraction Echocardiography
Item
8. left ventricular ejection fraction (lvef) determined by ventriculography or echocardiogram ≥ 40%
boolean
C0428772 (UMLS CUI [1,1])
C0596683 (UMLS CUI [1,2])
C0428772 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
Liver function | Renal function | Creatinine measurement, serum | Serum total bilirubin measurement | Alkaline phosphatase measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Infiltration Hepatic
Item
9. normal hepatic and renal function, with creatinine ≤ 2 mg/dl and bi ≤ 1.5 mg/dl, and alkaline phosphatase ≤ 2.5 x unl ; ast, alt ≤ 2.5 x unl (≤ 5 x unl if hepatic infiltration)
boolean
C0232741 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0201976 (UMLS CUI [3])
C1278039 (UMLS CUI [4])
C0201850 (UMLS CUI [5])
C0201899 (UMLS CUI [6])
C0201836 (UMLS CUI [7])
C0332448 (UMLS CUI [8,1])
C0205054 (UMLS CUI [8,2])
Radiopharmaceuticals
Item
1. prior treatment with radiopharmaceutical agents
boolean
C0182638 (UMLS CUI [1])
Lymphoma, HIV-Related
Item
2. hiv-associated lymphoma
boolean
C0085090 (UMLS CUI [1])
Human anti-mouse antibody | Human antichimeric Ab
Item
3. presence of human anti-mouse antibodies (hama) or anti-chimeric antibodies (haca)
boolean
C1291910 (UMLS CUI [1])
C1317433 (UMLS CUI [2])
Protocol Compliance Unable
Item
4. patient's inability to follow the protocol
boolean
C0525058 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Hypersensitivity yttrium-90-ibritumomab tiuxetan
Item
5. hypersensitivity to 90y-itritumomab tiuxetan
boolean
C0020517 (UMLS CUI [1,1])
C1134535 (UMLS CUI [1,2])
Pathology Severe Excludes Chemotherapy
Item
6. presence of severe pathologies that preclude chemotherapeutic treatment
boolean
C0677042 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0332196 (UMLS CUI [1,3])
C0392920 (UMLS CUI [1,4])
Pregnancy | Contraceptive methods Inappropriate | Pregnancy Risk
Item
7. pregnant women or pregnancy risk due to inappropriate contraceptive measures
boolean
C0032961 (UMLS CUI [1])
C0700589 (UMLS CUI [2,1])
C1548788 (UMLS CUI [2,2])
C0032961 (UMLS CUI [3,1])
C0035647 (UMLS CUI [3,2])
Breast Feeding
Item
8. breastfeeding women
boolean
C0006147 (UMLS CUI [1])