Diffuse Large B-Cell Lymphoma
Item
biopsy-proven diffuse large b-cell non-hodgkin's lymphoma
boolean
C0079744 (UMLS CUI [1])
Therapeutic procedure Non-Hodgkin Lymphoma | Non-Hodgkin's lymphoma recurrent | Non-Hodgkin Lymphoma Unresponsive to Treatment
Item
relapsed or refractory to previous therapy for non-hodgkin's lymphoma
boolean
C0087111 (UMLS CUI [1,1])
C0024305 (UMLS CUI [1,2])
C0854866 (UMLS CUI [2])
C0024305 (UMLS CUI [3,1])
C0205269 (UMLS CUI [3,2])
Measurable Disease Cross-sectional imaging | Measurable Disease Diameter Size
Item
measurable disease on cross sectional imaging that is at least 2 cm in the longest diameter
boolean
C1513041 (UMLS CUI [1,1])
C3824793 (UMLS CUI [1,2])
C1513041 (UMLS CUI [2,1])
C1301886 (UMLS CUI [2,2])
C0456389 (UMLS CUI [2,3])
ECOG performance status
Item
ecog performance score of 0,1 or 2
boolean
C1520224 (UMLS CUI [1])
Pregnancy Precaution Compliance behavior
Item
willing to follow the pregnancy precautions
boolean
C0032961 (UMLS CUI [1,1])
C1882442 (UMLS CUI [1,2])
C1321605 (UMLS CUI [1,3])
Laboratory test result abnormal
Item
any of the following laboratory abnormalities.
boolean
C0438215 (UMLS CUI [1])
Absolute neutrophil count
Item
absolute neutrophil count (anc) < 1,500 cells/mm3 (1.5 x 109/l).
boolean
C0948762 (UMLS CUI [1])
Platelet Count measurement
Item
platelet count < 60,000/mm3 (60 x 109/l).
boolean
C0032181 (UMLS CUI [1])
Aspartate aminotransferase increased | Alanine aminotransferase increased
Item
serum sgot/ast or sgpt/alt 5.0 x upper limit of normal (uln).
boolean
C0151904 (UMLS CUI [1])
C0151905 (UMLS CUI [2])
Serum total bilirubin measurement
Item
serum total bilirubin > 2.0 mg/dl (34 µmol/l).
boolean
C1278039 (UMLS CUI [1])
Indication Transplantation of autologous hematopoietic stem cell
Item
subjects who are candidates for and willing to undergo an autologous stem cell transplant.
boolean
C3146298 (UMLS CUI [1,1])
C1831743 (UMLS CUI [1,2])
Central nervous system lymphoma
Item
history of active cns lymphoma within the previous 3 months
boolean
C0742472 (UMLS CUI [1])
Deep Vein Thrombosis Prophylaxis Unwilling | Deep Vein Thrombosis Prophylaxis Unable
Item
subjects not willing or unable to take dvt prophylaxis
boolean
C0149871 (UMLS CUI [1,1])
C0199176 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
C0149871 (UMLS CUI [2,1])
C0199176 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
Malignant Neoplasms
Item
history of other malignancies within the past year
boolean
C0006826 (UMLS CUI [1])
HIV Seropositivity | Hepatitis B | Hepatitis C
Item
positive hiv or active hepatitis b or c
boolean
C0019699 (UMLS CUI [1])
C0019163 (UMLS CUI [2])
C0019196 (UMLS CUI [3])