Diabetes Mellitus, Non-Insulin-Dependent
Item
type 2 diabetes
boolean
C0011860 (UMLS CUI [1])
Insulin naive
Item
insulin naive
boolean
C0021641 (UMLS CUI [1,1])
C0919936 (UMLS CUI [1,2])
Antidiabetics Oral | Target Therapeutic Unavailable
Item
treatment with oral anti-diabetic drugs (oads) for at least 3 months and not achieving therapeutic targets
boolean
C0935929 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C1521840 (UMLS CUI [2,1])
C0302350 (UMLS CUI [2,2])
C0686905 (UMLS CUI [2,3])
Glycosylated hemoglobin A
Item
hba1c between 8% - 10.5%
boolean
C0019018 (UMLS CUI [1])
Secondary diabetes mellitus | Maturity onset diabetes mellitus in young
Item
secondary diabetes, mody (maturity onset diabetes of the young)
boolean
C0271640 (UMLS CUI [1])
C0342276 (UMLS CUI [2])
Insulin | Exclusion Insulin short-term Comorbidity
Item
previous treatment with insulin (except for short-term treatment with insulin for intercurrent illness as judged by the investigator)
boolean
C0021641 (UMLS CUI [1])
C2828389 (UMLS CUI [2,1])
C0021641 (UMLS CUI [2,2])
C0443303 (UMLS CUI [2,3])
C0009488 (UMLS CUI [2,4])
Proliferative retinopathy | Maculopathy Requirement Therapeutic procedure
Item
proliferative retinopathy, maculopathy requiring treatment,
boolean
C0339467 (UMLS CUI [1])
C0730362 (UMLS CUI [2,1])
C1514873 (UMLS CUI [2,2])
C0087111 (UMLS CUI [2,3])
Loss of hypoglycemic warning | Recurrent severe hypoglycemia
Item
hypoglycaemia unawareness as judged by the investigator, recurrent major hypoglycaemia
boolean
C0342317 (UMLS CUI [1])
C0342316 (UMLS CUI [2])
End Stage Liver Disease | Elevated liver enzymes | Chronic Kidney Failure Modification of diet in renal disease formula | Dialysis | Heart failure | Cardiovascular event | Event Cerebrovascular
Item
end stage liver disease (increased liver enzymes 4 fold), end stage renal disease assessed by mdrd (modification of diet in renal disease) less than 30 ml/min or dialysed patient, acute heart failure, any acute cardiovascular event or cerebrovascular event less than 6 months
boolean
C0745744 (UMLS CUI [1])
C0235996 (UMLS CUI [2])
C0022661 (UMLS CUI [3,1])
C3839656 (UMLS CUI [3,2])
C0011946 (UMLS CUI [4])
C0018801 (UMLS CUI [5])
C1320716 (UMLS CUI [6])
C0441471 (UMLS CUI [7,1])
C1880018 (UMLS CUI [7,2])
Disease Prognosis bad
Item
acute disease with poor prognosis
boolean
C0012634 (UMLS CUI [1,1])
C0278252 (UMLS CUI [1,2])
Alcoholic Intoxication, Chronic | Drug abuse | Mental disorders | Personality Disorders | Condition Interferes with Informed Consent | Condition Preventing Protocol Compliance
Item
history of alcoholism, drug abuse, or psychiatric disease or personality disorders likely to invalidate voluntary consent or to prevent good compliance with the trial protocol
boolean
C0001973 (UMLS CUI [1])
C0013146 (UMLS CUI [2])
C0004936 (UMLS CUI [3])
C0031212 (UMLS CUI [4])
C0348080 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C0021430 (UMLS CUI [5,3])
C0348080 (UMLS CUI [6,1])
C1292733 (UMLS CUI [6,2])
C0525058 (UMLS CUI [6,3])
Mental handicap Excludes Comprehension | Comprehension Unwilling | Language Barriers Exclude Comprehension | Mental handicap Excludes Compliance behavior | Compliance behavior Unwilling | Language Barriers Exclude Compliance behavior | Mini-mental state examination
Item
mental incapacity, unwillingness or language barrier precluding adequate understanding or co-operation (patients having a score of less than 15 in a previous mmse (mini-mental state examination) in the last six months) and any conditions as judged by the investigator
boolean
C1306341 (UMLS CUI [1,1])
C0332196 (UMLS CUI [1,2])
C0162340 (UMLS CUI [1,3])
C0162340 (UMLS CUI [2,1])
C0558080 (UMLS CUI [2,2])
C0237167 (UMLS CUI [3,1])
C0332196 (UMLS CUI [3,2])
C0162340 (UMLS CUI [3,3])
C1306341 (UMLS CUI [4,1])
C0332196 (UMLS CUI [4,2])
C1321605 (UMLS CUI [4,3])
C1321605 (UMLS CUI [5,1])
C0558080 (UMLS CUI [5,2])
C0237167 (UMLS CUI [6,1])
C0332196 (UMLS CUI [6,2])
C1321605 (UMLS CUI [6,3])
C0451306 (UMLS CUI [7])
Disability Legal | Limited function/disability Legal | Patient guardianship
Item
legal incapacity or limited legal capacity (patients under guardianship or curatorship)
boolean
C0231170 (UMLS CUI [1,1])
C1301860 (UMLS CUI [1,2])
C0497533 (UMLS CUI [2,1])
C1301860 (UMLS CUI [2,2])
C0030705 (UMLS CUI [3,1])
C0870627 (UMLS CUI [3,2])
Pharmaceutical Preparations Alzheimer's Disease | Memantine | Cholinesterase Inhibitors
Item
concomitant medication for alzheimers treatment (memantine, anticholinesterasique treatment)
boolean
C0013227 (UMLS CUI [1,1])
C0002395 (UMLS CUI [1,2])
C0025242 (UMLS CUI [2])
C0008425 (UMLS CUI [3])
Study Subject Participation Status
Item
participation in another clinical trial less than one month before inclusion in this trial
boolean
C2348568 (UMLS CUI [1])
Illness Requirement Hospitalization Repeated
Item
illness requiring repeated hospitalisation
boolean
C0221423 (UMLS CUI [1,1])
C1514873 (UMLS CUI [1,2])
C0019993 (UMLS CUI [1,3])
C0205341 (UMLS CUI [1,4])
Insulin allergy | Hypersensitivity Insulin Component | Insulin allergy Suspected | Hypersensitivity Insulin Component Suspected
Item
known or suspected allergy to the insulin or any compositional component
boolean
C0571622 (UMLS CUI [1])
C0020517 (UMLS CUI [2,1])
C0021641 (UMLS CUI [2,2])
C1705248 (UMLS CUI [2,3])
C0571622 (UMLS CUI [3,1])
C0750491 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0021641 (UMLS CUI [4,2])
C1705248 (UMLS CUI [4,3])
C0750491 (UMLS CUI [4,4])
Pharmaceutical Preparation Interferes with Glucose metabolism | Systemic Corticosteroid Therapy | Prednisone
Item
anticipated change or new use in concomitant medication known to interfere with glucose metabolism, such as systemic corticotherapy more than 5 mg/day (prednisone)
boolean
C0013227 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0596620 (UMLS CUI [1,3])
C4053960 (UMLS CUI [2])
C0032952 (UMLS CUI [3])
Condition Interferes with Study Subject Participation Status | Condition Interferes with Evaluation Research results
Item
any other condition that the investigator feels would interfere with trial participation or evaluation of results
boolean
C0348080 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C2348568 (UMLS CUI [1,3])
C0348080 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C1261322 (UMLS CUI [2,3])
C0683954 (UMLS CUI [2,4])
Terminal illness
Item
terminal illness
boolean
C0679247 (UMLS CUI [1])