Implants
Item
1. Implant placement at least 6 weeks and maximum 6 months prior enrolment
boolean
C0021102 (UMLS CUI [1])
Soft tissue augmentation
Item
2. Necessity of soft tissue augmentation in single tooth gap
boolean
C2732454 (UMLS CUI [1])
Teeth adjacent
Item
3. 2 teeth adjacent to each side of the defect have a mean BOP (Bleeding of probing) of < 30%
boolean
C1319068 (UMLS CUI [1])
Basic periodontal examination
Item
4. Basic periodontal examination (BPE <2)
boolean
C0332275 (UMLS CUI [1,1])
C0582103 (UMLS CUI [1,2])
Age
Item
5. 18 years or older
boolean
C0001779 (UMLS CUI [1])
Compliance
Item
6. Ability to comply with the study-related procedures such as exercising good oral hygiene and attending all follow-up procedures
boolean
C1321605 (UMLS CUI [1])
Understanding Ability
Item
7. Ability to fully understand the nature of the proposed surgery and ability to sign the informed consent form
boolean
C0582778 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
Control Group
Item
0. Healthy Volunteers
boolean
C0009932 (UMLS CUI [1])
Smoking Status
Item
1. Heavy smoker (> 10 cigarettes per day)
boolean
C1519386 (UMLS CUI [1])
Probing Depth
Item
2. Probing depth greater than 4 mm
boolean
C1317646 (UMLS CUI [1])
Insulin dependent diabetes
Item
3. Insulin dependent diabetes
boolean
C0011854 (UMLS CUI [1])
Contraindication
Item
4. General contraindications for dental and/or surgical treatment
boolean
C1301624 (UMLS CUI [1])
Prior Radiotherapy or Chemotherapy
Item
5. History of malignancy, radiotherapy, or chemotherapy for malignancy within the past five years
boolean
C0279134 (UMLS CUI [1])
C1514457 (UMLS CUI [2])
Contraceptive Methods
Item
6. Women of child bearing age, not using a standard accepted method of birth control
boolean
C0700589 (UMLS CUI [1])
Gynaecological Status
Item
7. Pregnancy or breast feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Medication affecting mucosal healing
Item
8. Previous and concurrent medication affecting mucosal healing in general (e.g. steroids, large doses of anti-inflammatory drugs)
boolean
C0013216 (UMLS CUI [1,1])
C1513724 (UMLS CUI [1,2])
Connective Tissue Diseases
Item
9. Disease affecting connective tissue metabolism (e.g. collagenases).
boolean
C0009782 (UMLS CUI [1])
Hypersensitivity to Collagen
Item
10. Allergy to collagen
boolean
C0020517 (UMLS CUI [1,1])
C0009325 (UMLS CUI [1,2])
Study Participation Status
Item
11. Participation in a clinical trial within the last six months
boolean
C2348568 (UMLS CUI [1])