Multiple Myeloma Symptomatic
Item
patients with newly diagnosed symptomatic mm (see appendix i)
boolean
C0026764 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
Patient eligible Transplantation of autologous hematopoietic stem cell
Item
patients should be eligible for ahct.
boolean
C0030705 (UMLS CUI [1,1])
C1548635 (UMLS CUI [1,2])
C1831743 (UMLS CUI [1,3])
Serum paraprotein measurement | Urine paraprotein measurement
Item
patients should have measurable serum or urine paraprotein.
boolean
C0585639 (UMLS CUI [1])
C0585640 (UMLS CUI [2])
Karnofsky Performance Status
Item
the performance status of the patients should be 70 or over by karnofsky performance scale
boolean
C0206065 (UMLS CUI [1])
Liver function | Renal function | Serum total bilirubin measurement | Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Creatinine measurement, serum
Item
adequate hepatic and renal function: serum bilirubin < 1.5 x the upper limit of normal (uln), serum alanine aminotransferase (alt)/aspartate aminotransaminase (ast) values < 2.5 x uln, serum creatinine < 1.5 x uln
boolean
C0232741 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C1278039 (UMLS CUI [3])
C0201836 (UMLS CUI [4])
C0201899 (UMLS CUI [5])
C0201976 (UMLS CUI [6])
Cardiac function | Cardiac ejection fraction Echocardiography | Cardiac ejection fraction Radionuclide Imaging Heart
Item
adequate cardiac function: ejection fraction > 40% by echocardiogram or radionuclide heart scan
boolean
C0232164 (UMLS CUI [1])
C0232174 (UMLS CUI [2,1])
C0013516 (UMLS CUI [2,2])
C0232174 (UMLS CUI [3,1])
C0034606 (UMLS CUI [3,2])
C0018787 (UMLS CUI [3,3])
Chemotherapy Multiple Myeloma | Dexamethasone U/day | Therapeutic radiology procedure Localized | Plasmapheresis Hyperviscosity syndrome
Item
prior chemotherapy for myeloma except 4 days of dexamethasone up to 40 mg per day or localized radiotherapy or plasmapheresis for the treatment of clinically significant hyperviscosity syndrome
boolean
C0392920 (UMLS CUI [1,1])
C0026764 (UMLS CUI [1,2])
C0011777 (UMLS CUI [2,1])
C0456683 (UMLS CUI [2,2])
C1522449 (UMLS CUI [3,1])
C0392752 (UMLS CUI [3,2])
C0032134 (UMLS CUI [4,1])
C0221030 (UMLS CUI [4,2])
Peripheral Neuropathy CTCAE Grades
Item
have a peripheral neuropathy of grade 2 or more within 14 days of enrollment.
boolean
C0031117 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Communicable Disease
Item
significant infection
boolean
C0009450 (UMLS CUI [1])