Age
Item
age 18-75 years.
boolean
C0001779 (UMLS CUI [1])
Smoldering myeloma Excluded | Monoclonal Gammopathy of Undetermined Significance Excluded | Primary amyloidosis Excluded | Multiple Myeloma | Amyloidosis
Item
patients must have their pathology reviewed and the diagnosis confirmed at stanford university medical center. patients with smoldering multiple myeloma, monoclonal gammopathy of unknown significance, or primary amyloidosis will be excluded from this study. patients with multiple myeloma and amyloidosis may be eligible for this trial, with approval by the principle investigator.
boolean
C1531608 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
C0026470 (UMLS CUI [2,1])
C2828389 (UMLS CUI [2,2])
C0268381 (UMLS CUI [3,1])
C2828389 (UMLS CUI [3,2])
C0026764 (UMLS CUI [4])
C0002726 (UMLS CUI [5])
Karnofsky Performance Status
Item
patients must have a karnofsky performance status > 70%.
boolean
C0206065 (UMLS CUI [1])
Carbon Monoxide Diffusing Capability Test
Item
dlco >=60% predicted.
boolean
C1516251 (UMLS CUI [1])
Alanine aminotransferase measurement | Aspartate aminotransferase measurement | Serum total bilirubin measurement
Item
alt and ast must be < 2x normal. total bilirubin less than 2 mg/dl.
boolean
C0201836 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C1278039 (UMLS CUI [3])
Creatinine measurement, serum | 24 hour renal creatinine clearance
Item
serum creatinine < 2.0 or 24-hour creatinine clearance e 60 ml/min.
boolean
C0201976 (UMLS CUI [1])
C4032392 (UMLS CUI [2])
HIV negative
Item
patients must be hiv negative.
boolean
C0481430 (UMLS CUI [1])
Pregnancy Excluded | Breast Feeding Excluded
Item
pregnant or lactating women will not be eligible to participate.
boolean
C0032961 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
C0006147 (UMLS CUI [2,1])
C2828389 (UMLS CUI [2,2])
Informed Consent
Item
patients must provide signed, informed consent.
boolean
C0021430 (UMLS CUI [1])
Exclusion Criteria | Mental disorder Severe | Illness Severe
Item
exclusion criteria:- severe psychological or medical illness
boolean
C0680251 (UMLS CUI [1])
C0004936 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
C0221423 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
autologous hematopoietic stem cell transplant
Item
patients who have undergone prior autologous hematopoietic cell transplantation will not be eligible for this study.
boolean
C2193200 (UMLS CUI [1])