Heart failure NYHA Interferes with daily activities Sometimes | Heart failure NYHA Limiting Severe daily activities
Item
subjects with heart failure that only sometimes interferes with daily activities (new york heart association [nyha] class ii (1)) or subjects with heart failure which severely limits daily activities (nyha class iii (2)) at baseline
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C0871707 (UMLS CUI [1,4])
C1998882 (UMLS CUI [1,5])
C0018801 (UMLS CUI [2,1])
C1275491 (UMLS CUI [2,2])
C0439801 (UMLS CUI [2,3])
C0205082 (UMLS CUI [2,4])
C0871707 (UMLS CUI [2,5])
Therapeutic procedure Appropriate Heart failure | Diuretics | Angiotensin-Converting Enzyme Inhibitors | Angiotensin II receptor antagonist | Adrenergic beta-1 Receptor Antagonists
Item
subject has appropriate medical therapy for heart failure (such as diuretic, angiotensin-converting enzyme (ace) inhibitor or angiotensin receptor blocker (arb) and beta blocker) for at least three months prior to the baseline evaluation.
boolean
C0087111 (UMLS CUI [1,1])
C1548787 (UMLS CUI [1,2])
C0018801 (UMLS CUI [1,3])
C0012798 (UMLS CUI [2])
C0003015 (UMLS CUI [3])
C0521942 (UMLS CUI [4])
C0304516 (UMLS CUI [5])
Pharmaceutical Preparations Stable | Tolerance Peptidyl-Dipeptidase A | Tolerance Angiotensin II receptor antagonist | Tolerance Adrenergic beta-1 Receptor Antagonists | Intolerance to Peptidyl-Dipeptidase A | Intolerance to Angiotensin II receptor antagonist | Intolerance to Adrenergic beta-1 Receptor Antagonists
Item
subject has been on stable medications maximized to the subject's tolerance of ace or arb and beta blockers as determined by the study investigator for at least 30 days prior to baseline evaluation. (stable is defined as no more than a 100% increase or a 50% decrease in dose.) if a subject is intolerant of ace, arb or beta blockers documented evidence must be available.
boolean
C0013227 (UMLS CUI [1,1])
C0205360 (UMLS CUI [1,2])
C0231197 (UMLS CUI [2,1])
C0022709 (UMLS CUI [2,2])
C0231197 (UMLS CUI [3,1])
C0521942 (UMLS CUI [3,2])
C0231197 (UMLS CUI [4,1])
C0304516 (UMLS CUI [4,2])
C1744706 (UMLS CUI [5,1])
C0022709 (UMLS CUI [5,2])
C1744706 (UMLS CUI [6,1])
C0521942 (UMLS CUI [6,2])
C1744706 (UMLS CUI [7,1])
C0304516 (UMLS CUI [7,2])
Hospitalization Quantity Due to Heart failure | Emergency department patient visit Quantity | Urgent Care Patient Visit Quantity | Heart failure Intravenous therapy Patient need for | Diuretics intravenous administration
Item
subject has had at least one heart failure-related hospitalization or at least one heart failure-related emergency department or urgent care visit necessitating heart failure-related intravenous therapy (e.g. diuretic administration) within 12 months prior to the baseline evaluation
boolean
C0019993 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,3])
C0018801 (UMLS CUI [1,4])
C0586082 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C2362545 (UMLS CUI [3,1])
C1512346 (UMLS CUI [3,2])
C1265611 (UMLS CUI [3,3])
C0018801 (UMLS CUI [4,1])
C0455142 (UMLS CUI [4,2])
C0686904 (UMLS CUI [4,3])
C0012798 (UMLS CUI [5,1])
C0013125 (UMLS CUI [5,2])
Heart beat Abnormal Rapid | Implantable defibrillator Patient need for
Item
to be considered for chronicle icd: subject has, or is at risk of having, a heart beat that is too fast and his/her doctor has determined he/she needs an implantable cardioverter defibrillator (icd).
boolean
C0425583 (UMLS CUI [1,1])
C0205161 (UMLS CUI [1,2])
C0456962 (UMLS CUI [1,3])
C0162589 (UMLS CUI [2,1])
C0686904 (UMLS CUI [2,2])
Heart Disease New York Heart Association Classification | Physical activity Limitation Slight | Physical activity Resulting in Fatigue | Physical activity Resulting in Palpitations | Physical activity Resulting in Dyspnea | Physical activity Resulting in Angina Pectoris
Item
1. class ii subjects with cardiac disease resulting in slight limitation of physical activity. they are comfortable at rest. ordinary physical activity results in fatigue, palpitation, dyspnea, or angina.
boolean
C0018799 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0026606 (UMLS CUI [2,1])
C0449295 (UMLS CUI [2,2])
C2937276 (UMLS CUI [2,3])
C0026606 (UMLS CUI [3,1])
C0332294 (UMLS CUI [3,2])
C0015672 (UMLS CUI [3,3])
C0026606 (UMLS CUI [4,1])
C0332294 (UMLS CUI [4,2])
C0030252 (UMLS CUI [4,3])
C0026606 (UMLS CUI [5,1])
C0332294 (UMLS CUI [5,2])
C0013404 (UMLS CUI [5,3])
C0026606 (UMLS CUI [6,1])
C0332294 (UMLS CUI [6,2])
C0002962 (UMLS CUI [6,3])
Heart Disease New York Heart Association Classification | Physical activity Limitation Marked | Physical activity Slight Resulting in Fatigue | Physical activity Slight Resulting in Palpitations | Physical activity Slight Resulting in Dyspnea | Physical activity Slight Resulting in Angina Pectoris
Item
2. class iii subjects with cardiac disease resulting in marked limitation of physical activity. they are comfortable at rest. less than ordinary activity causes fatigue, palpitation, dyspnea, or angina.
boolean
C0018799 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0026606 (UMLS CUI [2,1])
C0449295 (UMLS CUI [2,2])
C1706089 (UMLS CUI [2,3])
C0026606 (UMLS CUI [3,1])
C2937276 (UMLS CUI [3,2])
C0332294 (UMLS CUI [3,3])
C0015672 (UMLS CUI [3,4])
C0026606 (UMLS CUI [4,1])
C2937276 (UMLS CUI [4,2])
C0332294 (UMLS CUI [4,3])
C0030252 (UMLS CUI [4,4])
C0026606 (UMLS CUI [5,1])
C2937276 (UMLS CUI [5,2])
C0332294 (UMLS CUI [5,3])
C0013404 (UMLS CUI [5,4])
C0026606 (UMLS CUI [6,1])
C2937276 (UMLS CUI [6,2])
C0332294 (UMLS CUI [6,3])
C0002962 (UMLS CUI [6,4])
Heart failure Severe New York Heart Association Classification | Refractory heart failure New York Heart Association Classification
Item
subjects with severe heart failure who should always be resting (nyha class iv(3)) or stage d(4) refractory heart failure.
boolean
C0018801 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C1275491 (UMLS CUI [1,3])
C1281998 (UMLS CUI [2,1])
C1275491 (UMLS CUI [2,2])
Renal dysfunction Severe
Item
subjects with severe renal dysfunction.
boolean
C3279454 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Condition Severe Limiting Life Expectancy
Item
subjects with severe non-cardiac condition limiting 12-month survival.
boolean
C0348080 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
C0023671 (UMLS CUI [1,4])
Study Subject Participation Status Interferes with Research results
Item
subjects in concurrent studies that may confound the results.
boolean
C2348568 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0683954 (UMLS CUI [1,3])
Heart Disease New York Heart Association Classification | Heart Disease Resulting in Physical activity Discomfort | Heart failure Symptoms At rest | Angina Pectoris Symptoms At rest
Item
(3)class iv subjects with cardiac disease resulting in inability to carry on any physical activity without discomfort. symptoms of heart failure or the anginal syndrome may be present even at rest. if any physical activity is undertaken, discomfort is increased.
boolean
C0018799 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0018799 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C0026606 (UMLS CUI [2,3])
C2364135 (UMLS CUI [2,4])
C0018801 (UMLS CUI [3,1])
C1457887 (UMLS CUI [3,2])
C0443144 (UMLS CUI [3,3])
C0002962 (UMLS CUI [4,1])
C1457887 (UMLS CUI [4,2])
C0443144 (UMLS CUI [4,3])
Refractory heart failure New York Heart Association Classification | Therapeutic procedure Maximal | Symptoms Marked At rest
Item
(4)stage d refractory heart failure: patients who have marked symptoms at rest despite maximal medical therapy (e.g., those who are recurrently hospitalized or cannot be safely discharged from the hospital without specialized interventions)
boolean
C1281998 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C0806909 (UMLS CUI [2,2])
C1457887 (UMLS CUI [3,1])
C1706089 (UMLS CUI [3,2])
C0443144 (UMLS CUI [3,3])