Multi vessel coronary artery disease Ischemic Symptomatic | Revascularization Standard Inappropriate | Coronary Artery Bypass Surgery | Percutaneous Coronary Intervention | Left ventricular assist device | Heart Transplantation
Item
1. symptomatic ischaemic multi-vessel coronary artery disease (cad) not suitable for standard revascularization procedures such as cabg, pci, lvad, or heart transplant.
boolean
C1299432 (UMLS CUI [1,1])
C0475224 (UMLS CUI [1,2])
C0231220 (UMLS CUI [1,3])
C0581603 (UMLS CUI [2,1])
C1442989 (UMLS CUI [2,2])
C1548788 (UMLS CUI [2,3])
C0010055 (UMLS CUI [3])
C1532338 (UMLS CUI [4])
C0181598 (UMLS CUI [5])
C0018823 (UMLS CUI [6])
Ischemia Inducible Reversible | Left ventricle Percentage Single-Photon Emission-Computed Tomography
Item
2. area of reversible inducible ischaemia (>10% of lv on spect) performed not more than six months prior to study treatment.
boolean
C0022116 (UMLS CUI [1,1])
C0205263 (UMLS CUI [1,2])
C0205343 (UMLS CUI [1,3])
C1269892 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C0040399 (UMLS CUI [2,3])
Left ventricular ejection fraction | Therapeutic procedure Optimal
Item
3. lvef < 45% on optimal medical therapy.
boolean
C0428772 (UMLS CUI [1])
C0087111 (UMLS CUI [2,1])
C2698651 (UMLS CUI [2,2])
New York Heart Association Classification | Therapeutic procedure Optimal Stable
Item
4. nyha class ii- iv patient stable on optimal medical therapy for at least 30 days.
boolean
C1275491 (UMLS CUI [1])
C0087111 (UMLS CUI [2,1])
C2698651 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
Informed Consent | Compliance behavior
Item
5. written informed consent and agree to attend hospital appointments for 1 year.
boolean
C0021430 (UMLS CUI [1])
C1321605 (UMLS CUI [2])
Age
Item
6. male and females 18 to 80 years of age.
boolean
C0001779 (UMLS CUI [1])
Left ventricular aneurysm | Left ventricular thrombus
Item
1. left ventricular aneurysm or thrombus.
boolean
C0519097 (UMLS CUI [1])
C0587044 (UMLS CUI [2])
Aortic Aneurysm, Thoracic
Item
2. thoracic aortic aneurysm.
boolean
C0162872 (UMLS CUI [1])
Congenital heart disease
Item
3. congenital heart disease
boolean
C0152021 (UMLS CUI [1])
Angina, Unstable | Cardiomyopathies, Primary | Ventricular arrhythmia Life Threatening
Item
4. acute unstable angina, idiopathic cardiomyopathy, life-threatening ventricular arrhythmias, recent (less than 6 weeks).
boolean
C0002965 (UMLS CUI [1])
C0033141 (UMLS CUI [2])
C0085612 (UMLS CUI [3,1])
C2826244 (UMLS CUI [3,2])
Medical contraindication MRI | Medical contraindication Clinical Trial procedure
Item
5. contraindication to mri or any other study procedure.
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0008976 (UMLS CUI [2,2])
C0184661 (UMLS CUI [2,3])
Malignant Neoplasms | Skin carcinoma Low grade Resolved
Item
6. presence or history of cancer (except low grade and fully resolved non-melanoma skin malignancy).
boolean
C0006826 (UMLS CUI [1])
C0699893 (UMLS CUI [2,1])
C1282907 (UMLS CUI [2,2])
C1514893 (UMLS CUI [2,3])
Comorbidity Reducing Survival short-term | Comorbidity Interferes with Testing Functional
Item
7. any co-morbidity likely to reduce short- term survival or which may interfere with functional testing.
boolean
C0009488 (UMLS CUI [1,1])
C0392756 (UMLS CUI [1,2])
C0038952 (UMLS CUI [1,3])
C0443303 (UMLS CUI [1,4])
C0009488 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0039593 (UMLS CUI [2,3])
C0205245 (UMLS CUI [2,4])
Myocardial Infarction
Item
8. recent myocardial infarction < 6mths.
boolean
C0027051 (UMLS CUI [1])
Cerebrovascular accident
Item
9. cerebral vascular accident < 6mths.
boolean
C0038454 (UMLS CUI [1])
Hepatitis | Therapeutic immunosuppression | Hemodialysis
Item
10. active hepatitis, receiving immunosuppressive therapy, undergoing haemodialysis.
boolean
C0019158 (UMLS CUI [1])
C0021079 (UMLS CUI [2])
C0019004 (UMLS CUI [3])
Hematology finding abnormal
Item
11. clinically significant abnormal haematology.
boolean
C0475182 (UMLS CUI [1])
Alcoholic Intoxication, Chronic | Drug abuse | Emotional problems Severe | Abnormal behavior Severe | Psychiatric problem Severe
Item
12. recent history of alcoholism, drug abuse, or severe emotional, behavioural, or psychiatric problems.
boolean
C0001973 (UMLS CUI [1])
C0013146 (UMLS CUI [2])
C0677660 (UMLS CUI [3,1])
C0205082 (UMLS CUI [3,2])
C0233514 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C1306597 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Missing
Item
13. fertile women who are pregnant, nursing, or using no form of contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C1705492 (UMLS CUI [3,3])
Investigational New Drugs | Study Subject Participation Status
Item
14. receiving experimental medications or participating in another study within 12 weeks of enrolment into this study.
boolean
C0013230 (UMLS CUI [1])
C2348568 (UMLS CUI [2])