Age and depression
Item
in- or out-patients of 65 years of age or above fulfilling the international classification of diseases-tenth edition (icd-10) diagnosis of depressive single episode (f32.00-32.11. 32.8 or 32.9), depressive recurrent episode (f33.00-33.11, 33.8 or 33.9) or organic depressive episode (f06.32).
boolean
C0001779 (UMLS CUI [1])
C0011581 (UMLS CUI [2])
Hamilton Score
Item
the depressive state should be mild to moderate and reach a score on ham-d6 of ≥ 7 and ≤ 11
boolean
C0451203 (UMLS CUI [1])
Mini mental state exam
Item
patients with dementia can be included provided they have a mini mental state exam (mmse) score of ≥ 17
boolean
C2960235 (UMLS CUI [1])
Severe or psychotic depression
Item
patients with a current depressive episode of a severity reaching a score of ≥ 12 on the ham-d6-item depression factor. this is to exclude patients with severe or psychotic depression
boolean
C0588008 (UMLS CUI [1])
C0743072 (UMLS CUI [2])
Suicidal thoughts
Item
patients with suicidal thoughts or behaviour
boolean
C1948150 (UMLS CUI [1])
Contraindication to escitalopram
Item
patients with conditions where treatment with escitalopram is contraindicated: e.g. hypersensitivity to escitalopram or other contents of escitalopram tablets, concomitant treatment with non-selective, irreversible mono-amine-oxidase inhibitors, such as marplan
boolean
C1099456 (UMLS CUI [1,1])
C1301624 (UMLS CUI [1,2])
Failed treatment with escitalopram
Item
patients who in the current depressive episode have had a failed trial of treatment with escitalopram
boolean
C1099456 (UMLS CUI [1,1])
C0438286 (UMLS CUI [1,2])
Dementia
Item
co-morbid dementia with a severity corresponding to a score on the mmse of less than 17 as these patients will often be without the ability to give informed consent
boolean
C0497327 (UMLS CUI [1])
Sensory defects
Item
patients with sensory defects rendering psychometric assessment impossible, e.g. deafness, blindness, severe aphasia
boolean
C4068865 (UMLS CUI [1])
Language
Item
patients who cannot speak danish well enough to make psychometric assessment possible and meaningful
boolean
C1145677 (UMLS CUI [1])
Intellectual deficits
Item
patients with congenital or early acquired intellectual deficits
boolean
C0025362 (UMLS CUI [1])