patients being treated at the participating clinics
Item
only patients being treated at the participating clinics are eligible for this study
boolean
C0030705 (UMLS CUI [1,1])
C3489408 (UMLS CUI [1,2])
Enrollment; primary care facility; Specialty care unit | Geographic Locations
Item
patients must be enrolled at the primary or specialty care site, and be planning to continue living in the area of that clinic throughout the study
boolean
C1516879 (UMLS CUI [1,1])
C0814517 (UMLS CUI [1,2])
C4034258 (UMLS CUI [1,3])
C0017446 (UMLS CUI [2])
age
Item
patients must be 18-75 years old
boolean
C0001779 (UMLS CUI [1])
Major Depressive Disorder; Structured Clinical Interview; DSM-IV criteria for major depressive diagnosis documented
Item
patients must meet clinical criteria for mdd, based on clinical interview and dsm iv mdd checklist
boolean
C1269683 (UMLS CUI [1,1])
C0935589 (UMLS CUI [1,2])
C2199206 (UMLS CUI [1,3])
ham-d17 score
Item
screening ham-d17 score greater than or equal to 14
boolean
C3639712 (UMLS CUI [1])
informed consent
Item
patients must give written informed consent
boolean
C0021430 (UMLS CUI [1])
suicidal ideation
Item
patients with and without current suicidal ideation may be included in the study
boolean
C0424000 (UMLS CUI [1])
antidepressant agent
Item
patients must not have taken antidepressant medication for at least 2 weeks prior to screen (or 4 weeks in the case of fluoxetine).
boolean
C0003289 (UMLS CUI [1])
substance use disorder
Item
current substance abuse or dependence
boolean
C0038586 (UMLS CUI [1])
ssri treatment failures
Item
two past ssri treatment failures within the current episode, or last 2 years if chronic.
boolean
C0360105 (UMLS CUI [1,1])
C0162643 (UMLS CUI [1,2])
axis i diagnosis of bipolar disorder or schizophrenia
Item
patients with a current axis i diagnosis of bipolar disorder or schizophrenia
boolean
C0270287 (UMLS CUI [1,1])
C0005586 (UMLS CUI [1,2])
C0270287 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
primary axis i diagnosis of obsessive-compulsive disorder, anorexia nervosa or bulimia
Item
patients with a current primary axis i diagnosis of obsessive-compulsive disorder, anorexia nervosa or bulimia.
boolean
C0270287 (UMLS CUI [1,1])
C0028768 (UMLS CUI [1,2])
C0270287 (UMLS CUI [2,1])
C0003125 (UMLS CUI [2,2])
C0270287 (UMLS CUI [3,1])
C0006370 (UMLS CUI [3,2])
Sexually active; Childbearing Potential | Pregnancy | Breast Feeding
Item
women who are sexually active and who are not using adequate contraception, or who are pregnant, trying to become pregnant, or breast feeding.
boolean
C0241028 (UMLS CUI [1,1])
C3831118 (UMLS CUI [1,2])
C0032961 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
contraindication antidepressant medications
Item
patients with general medical conditions that contraindicate antidepressant medications
boolean
C1301624 (UMLS CUI [1,1])
C0003289 (UMLS CUI [1,2])
clinical status requires inpatient treatment
Item
patients whose clinical status requires inpatient treatment at the time of baseline interview.
boolean
C0449440 (UMLS CUI [1,1])
C0019993 (UMLS CUI [1,2])
able to speak english
Item
patients who cannot read and understand english since all research instruments are not yet translated and validated in spanish or other languages.
boolean
C0376245 (UMLS CUI [1])
antipsychotic agents
Item
some reports of ssri-induced akathisia-like states have found them to be more highly correlated with either concurrent or previous treatment with a neuroleptic, even in patients with no history of movement disorders therefore, patients who have taken an anti-psychotic medication within 4 months of the screening visit will be excluded from the study.
boolean
C0040615 (UMLS CUI [1])