Breast Carcinoma TNM clinical staging | Systemic Chemotherapy
Item
1. patients with newly diagnosed stage ii a-b or iii a-c breast cancers who are scheduled to start systemic chemotherapy.
boolean
C0678222 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
C1883256 (UMLS CUI [2])
Invasive carcinoma of breast
Item
2. patients must have a histological diagnosis of invasive breast cancer.
boolean
C0853879 (UMLS CUI [1])
Extent of disease Physical Examination | Imaging conventional | Mammography | Ultrasonography
Item
3. patients whose extent of disease is determined by physical examination and conventional imaging (mammography and sonography).
boolean
C0449279 (UMLS CUI [1,1])
C0031809 (UMLS CUI [1,2])
C0079595 (UMLS CUI [2,1])
C0439858 (UMLS CUI [2,2])
C0024671 (UMLS CUI [3])
C0041618 (UMLS CUI [4])
Chemotherapy Breast Carcinoma TNM clinical staging
Item
4. patients should have not received any previous chemotherapy for their newly diagnosed stage ii a-b or iii a-c breast cancer.
boolean
C0392920 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
C3258246 (UMLS CUI [1,3])
Age
Item
5. patients must be age 18 or older.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
6. ecog performance status 0-2.
boolean
C1520224 (UMLS CUI [1])
Malignant Neoplasms Free of
Item
7. patients with history of prior malignancies must be disease-free for at least 5 years prior of study entry.
boolean
C0006826 (UMLS CUI [1,1])
C0332296 (UMLS CUI [1,2])
Hematologic function | White Blood Cell Count procedure | Absolute neutrophil count | Platelet Count measurement | Hemoglobin measurement | Transfusion Acceptable
Item
8. normal hematological function: wbc > 3000/ul, absolute neutrophil count > 1500/ul, platelets > 100,000/ul, and hgb > 10 gms (transfusion to achieve hgb > 10 gms is acceptable).
boolean
C0221130 (UMLS CUI [1])
C0023508 (UMLS CUI [2])
C0948762 (UMLS CUI [3])
C0032181 (UMLS CUI [4])
C0518015 (UMLS CUI [5])
C0005841 (UMLS CUI [6,1])
C1879533 (UMLS CUI [6,2])
Serum total bilirubin measurement | Alanine aminotransferase measurement
Item
9. serum total bilirubin < 1.5 mg/dl and sgpt < 1.5 x normal.
boolean
C1278039 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
Informed Consent | Protocol Compliance
Item
10. patients must sign an informed consent indicating that they are aware of the investigational nature of the study in keeping with the policies of the hospital. the only acceptable consent form is the one attached at the end of this protocol.
boolean
C0021430 (UMLS CUI [1])
C0525058 (UMLS CUI [2])
Chemotherapy Breast Carcinoma
Item
1. patients who received previous chemotherapy for the newly diagnosed breast cancer.
boolean
C0392920 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
Lesion of breast Primary Evidence | Lesion of breast TNM clinical staging
Item
2. patients with no evidence of primary breast lesion (e.g., t0, tx).
boolean
C0567489 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C3887511 (UMLS CUI [1,3])
C0567489 (UMLS CUI [2,1])
C3258246 (UMLS CUI [2,2])
Disease Response Assessment Unwilling
Item
3. patients who are unwilling to come back for regular assessments of response.
boolean
C1704632 (UMLS CUI [1,1])
C1516048 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
Claustrophobia | Obesity | Equipment Weight Limit Not to Exceed
Item
4. patients with claustrophobia or obesity (exceeding the equipment weight limits).
boolean
C0008909 (UMLS CUI [1])
C0028754 (UMLS CUI [2])
C0014672 (UMLS CUI [3,1])
C0043100 (UMLS CUI [3,2])
C2349209 (UMLS CUI [3,3])
C1882121 (UMLS CUI [3,4])
Pregnancy | Breast Feeding | Gender Sexually active | Childbearing Potential Contraceptive methods Inadequate
Item
5. pregnant women, lactating women or sexually active women of childbearing potential who are not practicing adequate contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0079399 (UMLS CUI [3,1])
C0241028 (UMLS CUI [3,2])
C3831118 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0205412 (UMLS CUI [4,3])
Myocardial Infarction | Angina, Unstable | Congestive heart failure Uncontrolled | Cardiac Arrhythmia Uncontrolled
Item
6. patients with myocardial infarction within 6 months of study entry; unstable angina pectoris; uncontrolled congestive heart failure; uncontrolled arrhythmias.
boolean
C0027051 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C0018802 (UMLS CUI [3,1])
C0205318 (UMLS CUI [3,2])
C0003811 (UMLS CUI [4,1])
C0205318 (UMLS CUI [4,2])
Artificial cardiac pacemaker | Implants Metallic | Medical Device Incompatibility Problem 3 Tesla Magnetic Resonance Imaging Scanner
Item
7. patients with pacemakers or other metallic inserts that are not compatible with 3-t mr scanners.
boolean
C0030163 (UMLS CUI [1])
C0021102 (UMLS CUI [2,1])
C2986473 (UMLS CUI [2,2])
C1881693 (UMLS CUI [3,1])
C2985394 (UMLS CUI [3,2])
C0183115 (UMLS CUI [3,3])
Breast Disease Bilateral | Breast cancer recurrent
Item
8. patients with bilateral breast disease, and recurrent newly diagnosed breast cancer.
boolean
C0006145 (UMLS CUI [1,1])
C0238767 (UMLS CUI [1,2])
C0278493 (UMLS CUI [2])