Breast Carcinoma
Item
histologically confirmed breast cancer
boolean
C0678222 (UMLS CUI [1])
Disease TNM clinical staging
Item
stage iv disease
boolean
C0012634 (UMLS CUI [1,1])
C3258246 (UMLS CUI [1,2])
ERBB2 Protein Overexpression Immunohistochemistry | HER2 gene amplification Fluorescent in Situ Hybridization
Item
her2/neu-overexpression (3+ by immunohistochemistry and/or gene amplification by fluorescence in situ hybridization)
boolean
C1515560 (UMLS CUI [1,1])
C0021044 (UMLS CUI [1,2])
C1512127 (UMLS CUI [2,1])
C0162789 (UMLS CUI [2,2])
trastuzumab frequency | Herceptin Frequency | Chemotherapy Frequency | Disease Response | Stable Disease
Item
undergoing treatment with trastuzumab (herceptin®) (alone or together with chemotherapy) once weekly or 3 times weekly and has achieved responding or stable disease for ≥ 12 weeks
boolean
C0728747 (UMLS CUI [1,1])
C0376249 (UMLS CUI [1,2])
C0338204 (UMLS CUI [2,1])
C0376249 (UMLS CUI [2,2])
C0392920 (UMLS CUI [3,1])
C0376249 (UMLS CUI [3,2])
C1704632 (UMLS CUI [4])
C0677946 (UMLS CUI [5])
CNS metastases | Lesion of brain Parenchymal | Meningeal Carcinomatosis
Item
no cns metastases (i.e., brain parenchymal lesions and/or leptomeningeal carcinomatosis)
boolean
C0686377 (UMLS CUI [1])
C0221505 (UMLS CUI [2,1])
C0682552 (UMLS CUI [2,2])
C0220654 (UMLS CUI [3])
Neoplasm Metastasis Uncontrolled
Item
no uncontrolled metastatic disease at study entry
boolean
C0027627 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Hormone Receptor Status
Item
hormone receptor status
boolean
C0019929 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
Unspecified
Item
not specified
boolean
C0205370 (UMLS CUI [1])
Client Characteristics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Gender
Item
female
boolean
C0079399 (UMLS CUI [1])
Menopausal Status Unspecified
Item
menopausal status not specified
boolean
C1513126 (UMLS CUI [1,1])
C0205370 (UMLS CUI [1,2])
Karnofsky Performance Status
Item
karnofsky performance status 70-100%
boolean
C0206065 (UMLS CUI [1])
Medical contraindication MRI Scan
Item
no contraindication to mri scan
boolean
C1301624 (UMLS CUI [1,1])
C0917711 (UMLS CUI [1,2])
Therapeutic procedure
Item
prior concurrent therapy:
boolean
C0087111 (UMLS CUI [1])
disease characteristic
Item
see disease characteristics
boolean
C0599878 (UMLS CUI [1])