Lesion of liver Metastatic Due to colorectal disorder | Metastatic Neoplasm Chemotherapy failed | Disease Progression
Item
patients with metastatic liver lesions from colorectal disease who have failed or progressed on a chemotherapy regimen for metastatic disease.
boolean
C0577053 (UMLS CUI [1,1])
C0036525 (UMLS CUI [1,2])
C0678226 (UMLS CUI [1,3])
C2103078 (UMLS CUI [1,4])
C2939420 (UMLS CUI [2,1])
C0392920 (UMLS CUI [2,2])
C0231175 (UMLS CUI [2,3])
C0242656 (UMLS CUI [3])
Colorectal Carcinoma Evidence of | Biopsy
Item
biopsy proven evidence of colorectal cancer.
boolean
C0009402 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0005558 (UMLS CUI [2])
Lesion Quantity | Lesion size | Lesion Diameter Maximum
Item
patients with 4 or fewer lesions greater than 1 cm and with no single lesion greater than 7 cm in maximum diameter.
boolean
C0221198 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0449453 (UMLS CUI [2])
C0221198 (UMLS CUI [3,1])
C1301886 (UMLS CUI [3,2])
C0806909 (UMLS CUI [3,3])
Age
Item
age greater than or equal to 18 years.
boolean
C0001779 (UMLS CUI [1])
Informed Consent
Item
patients must be able to sign informed consent.
boolean
C0021430 (UMLS CUI [1])
Life Expectancy
Item
life expectancy greater than or equal to 3 months.
boolean
C0023671 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-2.
boolean
C1520224 (UMLS CUI [1])
Disease Extrahepatic | Secondary malignant neoplasm of liver | systemic therapy Disease Extrahepatic | Therapies, Investigational
Item
patients with extrahepatic disease in addition to their hepatic metastases are eligible and will receive systemic therapy for their extrahepatic disease following litx therapy.
boolean
C0012634 (UMLS CUI [1,1])
C1517058 (UMLS CUI [1,2])
C0494165 (UMLS CUI [2])
C1515119 (UMLS CUI [3,1])
C0012634 (UMLS CUI [3,2])
C1517058 (UMLS CUI [3,3])
C0949266 (UMLS CUI [4])
Chemotherapy ended | Chemotherapy Effects Patients Recovered
Item
off chemotherapy for 4 weeks. must have recovered from the chemotherapy effects.
boolean
C0392920 (UMLS CUI [1,1])
C2746065 (UMLS CUI [1,2])
C0392920 (UMLS CUI [2,1])
C1280500 (UMLS CUI [2,2])
C0030705 (UMLS CUI [2,3])
C0521108 (UMLS CUI [2,4])
Patients Excluded
Item
patients must be excluded if any of the following apply:
boolean
C0030705 (UMLS CUI [1,1])
C2828389 (UMLS CUI [1,2])
Indication Complete excision
Item
patients who are candidates for complete surgical resection.
boolean
C3146298 (UMLS CUI [1,1])
C0015250 (UMLS CUI [1,2])
Pregnancy | Breast Feeding | Urine pregnancy test negative Patient need for | Serum pregnancy test negative Patient need for
Item
pregnancy or breast-feeding. a negative pregnancy test (urine or serum) is required prior to enrollment.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0430057 (UMLS CUI [3,1])
C0686904 (UMLS CUI [3,2])
C0430061 (UMLS CUI [4,1])
C0686904 (UMLS CUI [4,2])
Allergic Reaction Serious Uncontrolled Contrast Media Investigational | anaphylaxis Contrast Media Investigational
Item
known uncontrollable serious reactions such as anaphylaxis, to the contrast agents used in this study.
boolean
C1527304 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C0205318 (UMLS CUI [1,3])
C0009924 (UMLS CUI [1,4])
C1517586 (UMLS CUI [1,5])
C0002792 (UMLS CUI [2,1])
C0009924 (UMLS CUI [2,2])
C1517586 (UMLS CUI [2,3])
Prothrombin time | Partial Thromboplastin Time measurement
Item
pt or ptt greater than 1.5x control.
boolean
C0033707 (UMLS CUI [1])
C0030605 (UMLS CUI [2])
Platelet Count measurement
Item
platelet count less than 100,000.
boolean
C0032181 (UMLS CUI [1])
White Blood Cell Count procedure
Item
wbc less than 2500/mm.
boolean
C0023508 (UMLS CUI [1])
Absolute neutrophil count
Item
neutrophils less than 2000/mm.
boolean
C0948762 (UMLS CUI [1])
Hemoglobin
Item
hemoglobin less than 9 g/dl.
boolean
C0019046 (UMLS CUI [1])
liver enzymes
Item
liver enzymes greater than 3 x uln.
boolean
C1287351 (UMLS CUI [1])
Serum total bilirubin measurement
Item
total bilirubin greater than 1.5 x uln.
boolean
C1278039 (UMLS CUI [1])
Creatinine measurement, serum
Item
serum creatinine greater than 2.5 x uln.
boolean
C0201976 (UMLS CUI [1])