Age
Item
age 8 - 35 years at the time of inclusion
boolean
C0001779 (UMLS CUI [1])
Body Weight
Item
body weight > 30 kg
boolean
C0005910 (UMLS CUI [1])
Diabetes Mellitus, Insulin-Dependent
Item
type 1 diabetes defined by: ada (american diabetes association) criteria or judgment of physician
boolean
C0011854 (UMLS CUI [1])
Diabetes disease length | fasting C-peptide level | Low C-peptide levels
Item
duration of diabetes: 1 month to 3* years (*the trialnet coordinating center will monitor fasting c-peptide levels as they are reported to ensure that a wide range of values is included. this review may result in widening the duration of diabetes window to allow for subjects with low c-peptide).
boolean
C0011847 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
C2208720 (UMLS CUI [2])
C4013229 (UMLS CUI [3])
Glycemic Index
Item
must maintain good glycemic control
boolean
C1136206 (UMLS CUI [1])
Protocol Compliance
Item
be willing to travel to a trialnet clinical center for a minimum of four separate visits that are spaced 3-10 days apart, and be willing to complete the study within a six week period.
boolean
C0525058 (UMLS CUI [1])
Pharmaceutical Preparations Affecting beta Cell function | Oral hypoglycemic | Adrenergic beta-2 Receptor Agonists
Item
actual treatment with drugs influencing beta cell function (e.g. oral hypoglycaemic agents, beta-2-receptor agonists)
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0030281 (UMLS CUI [1,3])
C0031843 (UMLS CUI [1,4])
C0359086 (UMLS CUI [2])
C2936789 (UMLS CUI [3])
Pharmaceutical Preparations Affecting Insulin Sensitivity | Steroids
Item
actual treatment with drugs influencing insulin sensitivity (e.g. steroids)
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0920563 (UMLS CUI [1,3])
C0038317 (UMLS CUI [2])
Comorbidity Significant Interferes with glucose metabolism | Disorder characterized by fever
Item
significant concomitant disease likely to interfere with glucose metabolism (e.g. febrile illness within the prior 3 days)
boolean
C0009488 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0521102 (UMLS CUI [1,3])
C0596620 (UMLS CUI [1,4])
C0743841 (UMLS CUI [2])
Poor compliance Expected
Item
expected poor compliance
boolean
C0032646 (UMLS CUI [1,1])
C1517001 (UMLS CUI [1,2])
Childbearing Potential Age Contraceptive methods | Pregnancy
Item
if a female of child-bearing age, currently pregnant or not using a form of birth control
boolean
C3831118 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C0700589 (UMLS CUI [1,3])
C0032961 (UMLS CUI [2])
Condition At risk Patients
Item
any other condition that by the judgement of the investigator may be potentially harmful to the patients
boolean
C0348080 (UMLS CUI [1,1])
C1444641 (UMLS CUI [1,2])
C0030705 (UMLS CUI [1,3])