Hamilton rating scale for depression
Item
21-item ham-d score of 20 or above.
boolean
C0451203 (UMLS CUI [1])
Antipsychotic Agents | Antidepressive Agents | Anticonvulsants | Mood stabilizing drug | Pharmaceutical Preparations Stable
Item
if currently taking antipsychotic, antidepressant, anticonvulsant, and/or mood-stabilizing medications, must be stable on the medication for at least three weeks prior to entering the study.
boolean
C0040615 (UMLS CUI [1])
C0003289 (UMLS CUI [2])
C0003286 (UMLS CUI [3])
C1276998 (UMLS CUI [4])
C0013227 (UMLS CUI [5,1])
C0205360 (UMLS CUI [5,2])
Antidepressive Agents Trials Quantity failed | Antidepressive Agents Dosage | Antidepressive Agents Duration
Item
at least 2 failed antidepressant medication trials of adequate dose and duration.
boolean
C0003289 (UMLS CUI [1,1])
C0008976 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0231175 (UMLS CUI [1,4])
C0003289 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0003289 (UMLS CUI [3,1])
C0449238 (UMLS CUI [3,2])
Age
Item
between 18 and 75 years of age.
boolean
C0001779 (UMLS CUI [1])
Pregnancy | Pregnancy, Planned
Item
not currently pregnant or trying to become pregnant.
boolean
C0032961 (UMLS CUI [1])
C0032992 (UMLS CUI [2])
Schizophrenia | Psychotic Disorders
Item
history of schizophrenia or other psychotic disorders.
boolean
C0036341 (UMLS CUI [1])
C0033975 (UMLS CUI [2])
Transcranial magnetic stimulation | Electroconvulsive Therapy
Item
transcranial magnetic stimulation treatment or ect in the 3 months prior to starting the study.
boolean
C0436548 (UMLS CUI [1])
C0013806 (UMLS CUI [2])
Vagus Nerve Stimulation
Item
history of vagus nerve stimulation treatment.
boolean
C2350432 (UMLS CUI [1])
Cardiovascular Disease Unstable | Hypertensive disease Unstable | Endocrine System Disease Unstable | Cardiovascular Disease untreated | Hypertensive disease untreated | Endocrine System Disease untreated
Item
no unstable or untreated cardiovascular disease, hypertension, or endocrine disorder.
boolean
C0007222 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0020538 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C0014130 (UMLS CUI [3,1])
C0443343 (UMLS CUI [3,2])
C0007222 (UMLS CUI [4,1])
C0332155 (UMLS CUI [4,2])
C0020538 (UMLS CUI [5,1])
C0332155 (UMLS CUI [5,2])
C0014130 (UMLS CUI [6,1])
C0332155 (UMLS CUI [6,2])
Oral Contraceptives Resulting in Mifepristone adverse reaction | Pharmaceutical Preparations Resulting in Mifepristone adverse reaction | Amiodarone | Clarithromycin | Erythromycin | Fluconazole | Fluvoxamine | Indinavir | Itraconazole | Ketoconazole | Metronidazole | Miconazole | nefazodone | Nelfinavir | Norfloxacin | Omeprazole | Quinine | Ritonavir | Saquinavir | Troleandomycin | zafirlukast | Carbamazepine | Dexamethasone | Ethosuximide | Phenobarbital | Phenytoin | Primidone | Rifabutin | Rifampin | troglitazone | Washout Period | Mifepristone
Item
current use of oral contraceptives or any other drug that may result in adverse drug-mifepristone interactions effects (including amiodarone, clarithromycin, erythromycin, fluconazole, fluvoxamine, indinavir, intraconazole, ketoconazole, metronidazole, miconazole, nefazodone, nelfinavir, norfloxacin, omeprazole, quinine, ritonavir, saquinavir, troleandomycin, zafirlukast, carbamazepine, dexamethasone, ethosuximide, phenobarbital, phenytoin, primidone, rifabutin, rifampin, troglitazone). a 30-day wash-out period for oral contraceptives is required before mifepristone begins.
boolean
C0009905 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0569852 (UMLS CUI [1,3])
C0013227 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C0569852 (UMLS CUI [2,3])
C0002598 (UMLS CUI [3])
C0055856 (UMLS CUI [4])
C0014806 (UMLS CUI [5])
C0016277 (UMLS CUI [6])
C0085228 (UMLS CUI [7])
C0376637 (UMLS CUI [8])
C0064113 (UMLS CUI [9])
C0022625 (UMLS CUI [10])
C0025872 (UMLS CUI [11])
C0025942 (UMLS CUI [12])
C0068485 (UMLS CUI [13])
C0525005 (UMLS CUI [14])
C0028365 (UMLS CUI [15])
C0028978 (UMLS CUI [16])
C0034417 (UMLS CUI [17])
C0292818 (UMLS CUI [18])
C0286738 (UMLS CUI [19])
C0041165 (UMLS CUI [20])
C0378466 (UMLS CUI [21])
C0006949 (UMLS CUI [22])
C0011777 (UMLS CUI [23])
C0015043 (UMLS CUI [24])
C0031412 (UMLS CUI [25])
C0031507 (UMLS CUI [26])
C0033148 (UMLS CUI [27])
C0140575 (UMLS CUI [28])
C0035608 (UMLS CUI [29])
C0245514 (UMLS CUI [30])
C1710661 (UMLS CUI [31])
C0026088 (UMLS CUI [32])
Mifepristone allergy | Allergic Reaction Pharmaceutical Preparations Chemical Structure Similar
Item
previous allergic reaction to mifepristone or drugs of similar chemical structure.
boolean
C0571161 (UMLS CUI [1])
C1527304 (UMLS CUI [2,1])
C0013227 (UMLS CUI [2,2])
C0220807 (UMLS CUI [2,3])
C2348205 (UMLS CUI [2,4])